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논문 기본 정보

자료유형
학술저널
저자정보
Youn-Kyoung Goo (Kyungpook National University School of Medicine) Won-Sik Shin (Shinsegae Women’s Hospital) Hye-Won Yang (Kyungpook National University School of Medicine) So-Young Joo (Kyungpook National University School of Medicine) Su-Min Song (Kyungpook National University School of Medicine) Jae-Sook Ryu (Hanyang University College of Medicine) Won-Myung Lee (Rosemary Hospital) Hyun-Hee Kong (Dong-A University College of Medicine) Won-Ki Lee (Kyungpook National University School of Medicine) Sang-Eun Lee (Korea Centers for Diseases Control and Prevention) Won-Ja Lee (Korea Centers for Diseases Control and Prevention) Dong-Il Chung (Kyungpook National University School of Medicine) Yeonchul Hong (Kyungpook National University School of Medicine)
저널정보
대한기생충학열대의학회 Parasites, Hosts and Diseases The Korean Journal of Parasitology Vol.54 No.1
발행연도
2016.2
수록면
75 - 80 (6page)

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This study explored epidemiological trends in trichomoniasis in Daegu, South Korea. Wet mount microscopy, PCR, and multiplex PCR were used to test for Trichomonas vaginalis in vaginal swab samples obtained from 621 women visiting 2 clinics in Daegu. Of the 621 women tested, microscopy detected T. vaginalis in 4 (0.6%) patients, PCR detected T. vaginalis in 19 (3.0%) patients, and multiplex PCR detected T. vaginalis in 12 (1.9%) patients. Testing via PCR demonstrated high sensitivity and high negative predictive value for T. vaginalis. Among the 19 women who tested positive for T. vaginalis according to PCR, 94.7% (18/19) reported vaginal signs and symptoms. Notably, more than 50% of T. vaginalis infections occurred in females younger than 30 years old, and 58% were unmarried. Multiplex PCR, which simultaneously detects pathogens from various sexually transmitted infections, revealed that 91.7% (11/12) of patients were infected with 2 or more pathogens. Mycoplasma hominis was the most prevalent co-infection pathogen with T. vaginalis, followed by Ureaplasma urealyticum and Chlamydia trachomatis. Our results indicate that PCR and multiplex PCR are the most sensitive tools for T. vaginalis diagnosis, rather than microscopy which has been routinely used to detect T. vaginalis infections in South Korea. Therefore, clinicians should take note of the high prevalence of T. vaginalis infections among adolescent and young women in order to prevent persistent infection and transmission of this disease.

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UCI(KEPA) : I410-ECN-0101-2016-513-002569696