지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.4
- 수록면
- 159 - 173 (15page)
이용수
초록· 키워드
오류제보하기
Crickets have been attracting considerable interest in the field of nutrition and toxicology due to the global exhaustion of food resulting from a growing population. The cricket is normally eaten in several countries after roasting, similar to the grasshopper; however, safety evaluation data on cricket powder is limited. Here, we performed general toxicity studies of cricket powder including a single, 2-week repeated dose range evaluation test, a 13-week repeated oral dose toxicity test in Sprague-Dawley rats, a single oral dose toxicity test in Beagle dogs, and a skin sensitization test in guinea pigs following the Organization for Economic Cooperation and Development test guidelines 406 and 408 in addition to Good Laboratory Practice. To investigate the NOAEL and target organs of cricket powder, Sprague-Dawley rats were allocated to 4 groups: vehicle control, 1,250 mg/kg, 2,500 mg/kg, 5,000 mg/kg dose test groups and cricket powder was administered over 13 weeks after single dose and dose range finding studies in rats based on the results of the single oral administration toxicity study in rats and Beagle dogs. The results of the study showed that the NOAEL of cricket powder was over 5,000 mg/kg for both sexes of rats without adverse effects in a 13-week repeated oral toxicity study and there was no skin hypersensitivity reaction. Therefore, our results reveal that crickets can be widely used as a new substitute food or nutrient resource.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (27)
참고문헌 신청
Ahn, M.Y., Lee, Y.W., Ryu, K.S., Lee, H.S., Kim, I.S., Kim, J.W. and Lim, S.S. (2004) Effects of water and methanol extracts of cricket (Gryllus bimaculatus) on alcohol metabolism. Korean J. Pharmacogn., 35, 175-178
Ahn, M.Y., Hwang, J.S. and Yun, E.Y. (2015) Gene expression profiling of glycosaminoglycan drived from G. bimaculatus in high fat dieted rat. FASEB J., 29, LB152
Ahn, M.Y., Han, J.W., Hwang, J.S., Yun, E.Y. and Lee, B.M. (2014) Anti-inflammatory effect of glycosaminoglycan derived from Gryllus bimaculatus (a type of cricket, insect) on adjuvant-treated chronic arthritis rat model. J. Toxicol. Environ. Health Part A, 77, 1332-1345
Kim, I.S., Ahn, M.Y., Ryu, K.S. and Lee, B.M. (2002) Acute oral toxicity of G. bimaculatus in rats. J. Toxicol. Pub. Health, 18, 397-400
OECD (1992) Test No. 406: Skin sensitisation in OECD Guidelines for the Testing of Chemicals, Section 4. Available from: http://www.oecd-ilibrary.org/environment/test-no-406-skinsensitisation_ 9789264070660-en (Accessed Dec. 27, 2012)
Ahn, M.Y., Hwang, J.S. and Yun, E.Y. (2015) Gene expression profiling of glycosaminoglycan drived from G. bimaculatus in high fat dieted rat. FASEB J., 29, LB152
Ahn, M.Y., Han, J.W., Hwang, J.S., Yun, E.Y. and Lee, B.M. (2014) Anti-inflammatory effect of glycosaminoglycan derived from Gryllus bimaculatus (a type of cricket, insect) on adjuvant-treated chronic arthritis rat model. J. Toxicol. Environ. Health Part A, 77, 1332-1345
Kim, I.S., Ahn, M.Y., Ryu, K.S. and Lee, B.M. (2002) Acute oral toxicity of G. bimaculatus in rats. J. Toxicol. Pub. Health, 18, 397-400
OECD (1992) Test No. 406: Skin sensitisation in OECD Guidelines for the Testing of Chemicals, Section 4. Available from: http://www.oecd-ilibrary.org/environment/test-no-406-skinsensitisation_ 9789264070660-en (Accessed Dec. 27, 2012)
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Acute and Repeated 28-Day Oral Dose Toxicity Studies of Thymus vulgaris L. Essential Oil in Rats
Toxicological Research
2019 .07
-
Toxicological assessment of Bromochlorophene: single and repeated-dose 28-day oral toxicity study in Sprague–Dawley rats
한국실험동물학회 학술발표대회 논문집
2021 .01
-
Acute and repeated dose 26-week oral toxicity study of 20(S)-ginsenoside Rg3 in Kunming mice and Sprague-Dawley rats
Journal of Ginseng Research
2020 .03
-
28-day repeated dose study of Chlorobutanol : Renal toxics
한국실험동물학회 학술발표대회 논문집
2021 .01
-
Repeated-dose 90-day oral toxicity study of GST in Sprague-Dawley rats
Environmental Analysis Health and Toxicology
2022 .06
-
Single oral dose toxicity test of DMZ-33, 71 and 77 in Balb/c mice
한국실험동물학회 학술발표대회 논문집
2022 .01
-
A Study on the Single-dose Oral Toxicity of Super Key in Sprague-Dawley Rats
Journal of Pharmacopuncture
2015 .01
-
26-week repeated-dose oral toxicity study of Perfluoroheptanoic acid in Sprague-Dawley rats
환경독성보건학회 심포지엄 및 학술대회
2022 .10
-
Sprague-Dawley 랫드를 이용한 땃두릅나무 열수추출물 분말의 단회 경구투여 독성시험 및 4주 반복 경구투여 용량 결정 시험
생약학회지(Korean Journal of Pharmacognosy)
2019 .09
-
Effect of 28-day repeated oral dose toxicity of aluminum chloride(AlCl3) in rat
한국실험동물학회 학술발표대회 논문집
2022 .07
-
Single dose oral toxicity study of a water extract of Gekko gecko in Sprague-Dawley rats
Journal of Biomedical and Translational Research
2024 .06
-
Repeated-dose 28-day dermal toxicity study of TiO₂ catalyst (GST) in Sprague-Dawley rats
Environmental Analysis Health and Toxicology
2022 .06
-
2-Week Repeated Dose Toxicity of a Fermented Ginseng Extract, GBCK25, Administered by Oral Gavage in SD Rats
한국실험동물학회 학술발표대회 논문집
2016 .08
-
4-week Repeated Dose Oral Toxicity Study of Copper Nanoparticles in Rats
한국실험동물학회 학술발표대회 논문집
2015 .08
-
Single-dose acute toxicity of orally administered Super-Neophensan containing florfenicol and acetaminophen in Sprague-Dawley rats
예방수의학회지
2017 .12
-
산수유, 보골지 복합추출물의 Sprague-Dawley rat를 이용한 단회경구투여 독성시험
대한본초학회지(본초분과학회지)
2019 .01
-
Repeated dose 90-day oral toxicity of Kaolin in Spraque-Dawley (SD) rats
한국실험동물학회 학술발표대회 논문집
2021 .07
-
귀뚜라미 분말에 의한 직업성천식 1예
Allergy Asthma & Respiratory Diseases
2024 .01
-
Two-Week Repeated Dose Toxicity of Atractylodis Rhizoma Alba in F344 Rats
Natural Product Sciences
2016 .09
-
Comparative analysis of historical background data of 13-week repeated toxicity study between Sprague-Dawley rat and Fischer 344 rat
한국실험동물학회 학술발표대회 논문집
2022 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2016-513-002786497