지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 환경독성보건학회 Environmental Analysis Health and Toxicology Environmental Health and Toxicology Vol.30
- 발행연도
- 2015.12
- 수록면
- 84 - 102 (19page)
이용수
이 논문의 연구 히스토리 (2)
2015
A meta-analysis of exposure to particulate matter and adverse birth outcomes
Di
,
ga Kuma
,
Lamichhane
외 3명
Environmental Analysis Health and Toxicology
2015.12
학술저널
A meta-analysis of exposure to particulate matter and adverse birth outcomes
Di
,
ga Kuma
,
Lamichhane
외 8명
환경독성보건학회 심포지엄 및 학술대회
2015.10
학술대회자료
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초록· 키워드
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Objectives: The objective of this study was to conduct a systematic review to provide summarized evidence on the association between maternal exposure to particulate air pollution and birth weight (BW) and preterm birth (PTB) after taking into consideration the potential confounding effect of maternal smoking.
Methods: We systematically searched all published cohort and case-control studies examining BW and PTB association with particulate matter (PM, less than or equal to 2.5 μm and 10.0 μm in diameter, PM2.5 and PM10, respectively) from PubMed and Web of Science, from January 1980 to April 2015. We extracted coefficients for continuous BW and odds ratio (OR) for PTB from each individual study, and meta-analysis was used to combine the coefficient and OR of individual studies. The methodological quality of individual study was assessed using a standard protocol proposed by Downs and Black. Forty-four studies met the inclusion criteria.
Results: In random effects meta-analyses, BW as a continuous outcome was negatively associated with 10 μg/m3 increase in PM10 (-10.31 g; 95% confidence interval [CI], -13.57 to -3.13 g; I-squared=0%, p =0.947) and PM2.5 (-22.17 g; 95% CI, -37.93 to -6.41 g; Isquared= 92.3%, p <0.001) exposure during entire pregnancy, adjusted for maternal smoking. A significantly increased risk of PTB per 10 μg/m3 increase in PM10 (OR, 1.23; 95% CI, 1.04 to 1.41; I-squared=0%, p =0.977) and PM2.5 (OR, 1.14; 95% CI, 1.06 to 1.22; I-squared=92.5%, p <0.001) exposure during entire pregnancy was observed. Effect size of change in BW per 10 μg/m3 increase in PM tended to report stronger associations after adjustment for maternal smoking.
Conclusions: While this systematic review supports an adverse impact of maternal exposure to particulate air pollution on birth outcomes, variation in effects by exposure period and sources of heterogeneity between studies should be further explored.
Methods: We systematically searched all published cohort and case-control studies examining BW and PTB association with particulate matter (PM, less than or equal to 2.5 μm and 10.0 μm in diameter, PM2.5 and PM10, respectively) from PubMed and Web of Science, from January 1980 to April 2015. We extracted coefficients for continuous BW and odds ratio (OR) for PTB from each individual study, and meta-analysis was used to combine the coefficient and OR of individual studies. The methodological quality of individual study was assessed using a standard protocol proposed by Downs and Black. Forty-four studies met the inclusion criteria.
Results: In random effects meta-analyses, BW as a continuous outcome was negatively associated with 10 μg/m3 increase in PM10 (-10.31 g; 95% confidence interval [CI], -13.57 to -3.13 g; I-squared=0%, p =0.947) and PM2.5 (-22.17 g; 95% CI, -37.93 to -6.41 g; Isquared= 92.3%, p <0.001) exposure during entire pregnancy, adjusted for maternal smoking. A significantly increased risk of PTB per 10 μg/m3 increase in PM10 (OR, 1.23; 95% CI, 1.04 to 1.41; I-squared=0%, p =0.977) and PM2.5 (OR, 1.14; 95% CI, 1.06 to 1.22; I-squared=92.5%, p <0.001) exposure during entire pregnancy was observed. Effect size of change in BW per 10 μg/m3 increase in PM tended to report stronger associations after adjustment for maternal smoking.
Conclusions: While this systematic review supports an adverse impact of maternal exposure to particulate air pollution on birth outcomes, variation in effects by exposure period and sources of heterogeneity between studies should be further explored.
목차
Introduction
Materials and Methods
Results
Discussion
Conclusion
References
참고문헌 (72)
참고문헌 신청
Sapkota A. / 2012 / Exposure to particulate matter and adverse birth outcomes : a comprehensive review and meta-analysis / Air Qual Atmos Health 5(4):369~381
Srám RJ. / 2005 / Ambient air pollution and pregnancy outcomes : a review of the literature / Environ Health Perspect 113(4):375~382
Stieb DM. / 2012 / Ambient air pollution, BW and preterm birth : a systematic review and meta-analysis / EnvironRes 117:100~111
Behrman RE / 2007 / Committee on Understanding Premature Birth and Assuring Healthy Outcomes. Preterm birth: causes, consequences, and prevention / National Academies Press :311~432
Wilcox AJ / 2001 / On the importance--and the unimportance--of birthweight / Int J Epidemiol 30(6):1233~1241
Srám RJ. / 2005 / Ambient air pollution and pregnancy outcomes : a review of the literature / Environ Health Perspect 113(4):375~382
Stieb DM. / 2012 / Ambient air pollution, BW and preterm birth : a systematic review and meta-analysis / EnvironRes 117:100~111
Behrman RE / 2007 / Committee on Understanding Premature Birth and Assuring Healthy Outcomes. Preterm birth: causes, consequences, and prevention / National Academies Press :311~432
Wilcox AJ / 2001 / On the importance--and the unimportance--of birthweight / Int J Epidemiol 30(6):1233~1241
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UCI(KEPA) : I410-ECN-0101-2017-539-000798897