지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.12
- 수록면
- 253 - 257 (5page)
이용수
초록· 키워드
오류제보하기
Exposure assessment for three major active ingredients used for humidifier disinfectants, polyhexamethylene guanidine (PHMG), oligo(2-(2-ethoxy)ethoxyethyl guanidinium chloride (PGH), and 5-chloro-2-methylisothiazol-3(2H)-one/2-methylisothiazol-3(2H)-one (CMIT/MIT) mixture, was conducted in a bedroom using an air sampler for a refined risk assessment. The experimental site was select-ed to reflect consumer exposure conditions. Aerosols formed by a humidifier were sampled during 8 hr at 7.5 L/min. Absorbed PHMG and PGH by the sampler were quantified using a spectrophotometric method, and high performance liquid chromatography-ultraviolet detection was used for CMIT/MIT. Three exposure scenarios were assumed for adding humidifier disinfectants to the humidifier water at 1, 2, and 10 times the volume recommended by the product suppliers, and the humidifier was on at its maximum rate of producing aerosols in order to consider reasonable worst-cases. The sampled mass of PHMG and PGH ranged 200 to 2,800 μg and 140 to 1,900 μg, respectively, under different exposure conditions, whereas the absorbed mass of CMIT/MIT was barely detected at the detection limit of 0.11/0.29 mg/L, only at 10 times the recommended level. The resulting risk quotients for PHMG and PGH ranged 1,400 to 20,000 and 1,000 to 13,000, indicating that health risks could be significant. For CMIT/MIT mixture, risk quotients were much smaller than estimated by assuming that they are conservative in the indoor environment, probably due to oxidative reactions. The refined exposure assessment presented here may provide a useful tool for assessing risks posed by active ingredients in spray-type biocidal products.
목차
등록된 정보가 없습니다.
참고문헌 (18)
참고문헌 신청
1. [학술지(정기간행물)] - Korea Centers for Disease Control and Prevention / 2011 / Interim report of epidemiological investigation on lung injury with unknown cause in Korea / Public Health Wkly. Rep 4 : 817 ~ 818
2. [인터넷자원] - Bae JS / / 18 killed by humidifier sterilizer: civic group
3. [인터넷자원] - Korea Ministry of Health and Welfare / / Order for withdrawal of six humidifier disinfectant products from the market issued
4. [학술지(정기간행물)] - Lee JH / 2012 / Fatal misuse of humidifier disinfectants in Korea: importance of screening risk assessment and implications for management of chemicals in consumer products / Environ. Sci. Technol 46 : 2498 ~ 2500
5. [단행본] - US Environmental Protection Agency / 1986 / Method for the determination of phenol and methylphenols (Cresols) in ambient air using high performance liquid chromatography / US Environmental Protection Agency
2. [인터넷자원] - Bae JS / / 18 killed by humidifier sterilizer: civic group
3. [인터넷자원] - Korea Ministry of Health and Welfare / / Order for withdrawal of six humidifier disinfectant products from the market issued
4. [학술지(정기간행물)] - Lee JH / 2012 / Fatal misuse of humidifier disinfectants in Korea: importance of screening risk assessment and implications for management of chemicals in consumer products / Environ. Sci. Technol 46 : 2498 ~ 2500
5. [단행본] - US Environmental Protection Agency / 1986 / Method for the determination of phenol and methylphenols (Cresols) in ambient air using high performance liquid chromatography / US Environmental Protection Agency
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UCI(KEPA) : I410-ECN-0101-2017-539-001538839