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Preparation and Characterization of AEMA Grafted PCL Nanofibers Using Gamma-ray Irradiation
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감마선 이용 AEMA 도입 PCL 나노섬유의 제조 및 특성분석

논문 기본 정보

Type
Academic journal
Author
Da-Eun Seo (한국원자력연구원) Sung In Jeong (한국원자력연구원) Jong-Seok Park (한국원자력연구원) Hui-Jeong Gwon (한국원자력연구원) Sung-Jun An (한국원자력연구원) Byoung Hun Lee (한국원자력연구원) Don-Sun Im (한국원자력연구원) Heungsoo Shin (한양대학교) Youn-Mook Lim (한국원자력연구원)
Journal
The Polymer Society Of Korea Polymer Korea Vol.41 No.1 KCI Accredited Journals SCIE
Published
2017.1
Pages
143 - 150 (8page)
DOI
10.7317/pk.2017.41.1.143

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Preparation and Characterization of AEMA Grafted PCL Nanofibers Using Gamma-ray Irradiation
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Polycaprolactone (PCL) has been applied to tissue engineering because it has excellent biocompatibility and biodegradable properties. However, there is a limit to hydrophobic surface and low cell adhesion, therefore the PCL requires surface modification for increasing hydrophilicity and cell adhesion capacity. In this study, PCL films and nanofibers were manufactured by solvent casting and electrospinning, respectively. They were modified by 2-aminoethylmethacrylate (AEMA) that had hydrophilicity and amine groups of positive charge using gamma-irradiation. The surface properties of AEMA-grafted PCL films and nanofibers were confirmed by ATR-FTIR, and amine groups were increased by surface area and gamma-irradiation dose. A significantly higher amount of negative-charged proteins adhered to hydrophilic and cationic surface of AEMA-grafted PCL nanofibers than that of AEMA-grafted PCL films, because of increased amine groups and electrostatic interaction. The results show that AEMA-grafted PCL nanofibers are possible to apply tissue engineering scaffolds.
#polycaprolactone #2-aminoethylmethacrylate #surface modification #positive charge #gamma irradiation

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Abstract
서론
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결과 및 토론
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References (35)

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[학술지(정기간행물)] - I. K. Ko / 2011 / / Polymer Science and Technology 22 : 17 ~ google schola [학술지(정기간행물)] - Y. M. Shin / 2007 / / Polymer Science and Technology 18 : 458 ~ google schola [학술지(정기간행물)] - J. H. Lee / 2011 / / KSBMB News 9 : 32 ~ google schola [학술지(정기간행물)] - J. M. Bourget / 2012 / / Biomaterials 33 : 9205 ~ google schola [학술지(정기간행물)] - P. Karuppuswamy / 2014 / / Appl. Surf. Sci 322 : 162 ~ google schola

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UCI(KEPA) : I410-ECN-0101-2017-578-001977497