Human Cases of Fascioliasis in Fujian Province, China

Lin Ai; Yu-Chun Cai; Yan Lu; Jia-Xu Chen; Shao-Hong Chen

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자료유형: 학술저널

저자정보: Lin Ai (National Health and Family Planning Commission) Yu-Chun Cai (National Health and Family Planning Commission) Yan Lu (National Health and Family Planning Commission) Jia-Xu Chen (National Health and Family Planning Commission) Shao-Hong Chen (National Health and Family Planning Commission)

저널정보: 대한기생충학열대의학회 Parasites, Hosts and Diseases The Korean Journal of Parasitology Vol.55 No.1

발행연도: 2017.2

수록면: 55 - 60 (6page)

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Fascioliasis is a foodborne zoonotic parasitic disease. We report 4 cases occurring in the same family, in whom diagnosis of acute fascioliasis was established after series of tests. One case was hospitalized with fever, eosinophilia, and hepatic lesions. MRI showed hypodense changes in both liver lobes. The remaining 3 cases presented with the symptom of stomachache only. Stool analysis was positive for Fasciola eggs in 2 adult patients. The immunological test and molecular identification of eggs were confirmed at the National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, China. The results of serological detection were positive in all the 4 patients. DNA sequencing of PCR products of the eggs demonstrated 100% homology with ITS and cox1 of Fasciola hepatica. The conditions of the patients were not improved by broad-spectrum anti-parasitic drugs until administration of triclabendazole.

#Fasciola hepatica #human case #diagnosis #triclabendazole

참고문헌 (34)

참고문헌 신청

[학술지(정기간행물)] - Mas-Coma S / 2005 / Fascioliasis and other plant-borne trematode zoonoses / Int J Parasitol 35 : 1255 ~ 1278

[학술지(정기간행물)] - Mas-Coma S / 2014 / Fascioliasis / Adv Exp Med Biol 766 : 77 ~ 114

[학술지(정기간행물)] - Mas-Coma S / 2009 / Chapter 2. Fasciola, lymnaeids and human fascioliasis, with a global overview on disease transmission, epidemiology, evolutionary genetics, molecular epidemiology and control / Adv Parasitol 69 : 41 ~ 146

[학술지(정기간행물)] - Ah Jin Kim / 2015 / Ectopic Human Fasciola hepatica Infection by an Adult Worm in the Mesocolon / The Korean Journal of Parasitology 53 (6) : 725 ~ 730

[학술지(정기간행물)] - Qureshi AW / 2016 / Epidemiological analysis of human fascioliasis in northeastern Punjab, Pakistan / Acta Trop 156 : 157 ~ 164

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이 논문의 저자 정보

Lin Ai

소속기관 Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research)