Seroprevalence of Toxoplasma gondii among HIV Patients in Jahrom, Southern Iran

Hassan Rezanezhad; Fateme Sayadi; Enayatollah Shadmand; Seyed Dawood Mousavi Nasab; Hadi Rezaei Yazdi; Kavous Solhjoo; Akbar Kazemi; Monireh Maleki; Abbas Ahmadi Vasmehjani

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저자정보: Hassan Rezanezhad (Jahrom University of Medical Sciences) Fateme Sayadi (Jahrom University of Medical Sciences) Enayatollah Shadmand (Jahrom University of Medical Sciences) Seyed Dawood Mousavi Nasab (Jahrom University of Medical Sciences) Hadi Rezaei Yazdi (Jahrom University of Medical Sciences) Kavous Solhjoo (Jahrom University of Medical Sciences) Akbar Kazemi (Jahrom University of Medical Sciences) Monireh Maleki (Tehran University of Medical Sciences) Abbas Ahmadi Vasmehjani (Jahrom University of Medical Sciences)

저널정보: 대한기생충학열대의학회 Parasites, Hosts and Diseases The Korean Journal of Parasitology Vol.55 No.1

발행연도: 2017.2

수록면: 99 - 103 (5page)

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Toxoplasma gondii is an important opportunistic agent especially in immunocompromised hosts and can cause significant morbidity and mortality. Hence, detection and monitoring of anti-Toxoplasma antibodies are of a great interest in HIV-infected patients. A study on the prevalence of toxoplasmosis and associated risk factors was carried out among HIV-infected patients in Jahrom, southern Iran. The prevalence of anti-Toxoplasma IgG antibodies was 21.1% in HIV-infected patients by ELISA. PCR was performed on all of the samples, and 1 of the blood samples was positively detected. Among the HIV patients, anti-Toxoplasma IgG antibodies were significantly higher in age group of 30-39 years old P=0.05). The seroprevalence of toxoplasmosis in patients with CD4<SUP>+</SUP><100 cells/μl was 33.3% that was significantly higher than the other groups (P=0.042) with or without IgG antibodies. The CD4<SUP>+</SUP> count mean of seropositive patients was lower than that of seronegative patients. The seroprevalence of toxoplasmosis in patients with highly active antiretroviral therapy was significantly less than patients without therapy (P=0.02). In conclusion, this study showed low seroprevalence of latent toxoplasmosis among HIV-infected patients in the region and confirmed the need for intensifying prevention efforts among this high-risk population and also the risk of toxoplasmosis reactivation which could be important among this population.

#Toxoplasma gondii #HIV patient #seroprevalence #PCR #IgG #Jahrom #Iran

참고문헌 (20)

참고문헌 신청

[학술지(정기간행물)] - Grant IH / 1990 / Toxoplasma gondii serology in HIV-infected patients : the development of central nervous system toxoplasmosis in AIDS / AIDS 4 : 519 ~ 522

[학술지(정기간행물)] - Mamidi A / 2002 / Central nervous system infections in individuals with HIV-1 infection / J Neurovirol 8 : 158 ~ 167

[학술지(정기간행물)] - Machala L / 2009 / Antibody response of HIV-infected patients to latent, cerebral and recently acquired toxoplasmosis / Eur J Clin Microbiol Infect Dis 28 : 179 ~ 182

[학술지(정기간행물)] - Daryani A / 2014 / Seroprevalence of Toxoplasma gondii in the Iranian general population : a systematic review and meta-analysis / Acta Trop 137 : 185 ~ 194

[학술지(정기간행물)] - Jones JL / 2003 / Toxoplasmosis-related knowledge and practices among pregnant women in the United States / Infect Dis Obstet Gynecol 11 : 139 ~ 145

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