지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.4
- 수록면
- 159 - 165 (7page)
이용수
초록· 키워드
오류제보하기
Vivax malaria reemerged in Korea in 1993 and the outbreak has been continued with fluctuating numbers of annual indigenous cases. Understanding the nature of the genetic population of Plasmodium vivax circulating in Korea is beneficial for the knowledge of the nationwide parasite heterogeneity and in the implementation of malaria control programs in the country. Previously, we analyzed polymorphic nature of merozoite surface protein-1 (MSP-1) and MSP-3α in Korean P. vivax population and identified the Korean P. vivax population has been diversifying rapidly, with the appearance of parasites with new genetic subtypes, despite the recent reduction of the disease incidence. In the present study, we developed simple PCR-RFLP methods for rapid subtyping of MSP-1 and MSP-3α of Korean P. vivax isolates. These PCR-RFLP methods were able to easily distinguish each subtype of Korean P. vivax MSP-1 and MSP-3α with high accuracy. The PCR-RFLP subtyping methods developed here would be easily applied to massive epidemiological studies for molecular surveillance to understand genetic population of P. vivax and to supervise the genetic variation of the parasite circulating in Korea.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
ACKNOWLEDGMENT
REFERENCES
참고문헌 (31)
참고문헌 신청
[학술지(정기간행물)] - Mendis K / 2001 / The neglected burden of Plasmodium vivax malaria / Am J Trop Med Hyg 64 : 97 ~ 106
[학술지(정기간행물)] - Guerra CA / 2007 / Assembling a global database of malaria parasite prevalence for the Malaria Atlas Project / Malar J 6 : 17 ~
[학술지(정기간행물)] - Soh CT / 1985 / Current status of malaria in Korea / Yonsei Rep Trop Med 16 : 11 ~ 18
[학술지(정기간행물)] - Kim TS / 2013 / Decreasing incidence of Plasmodium vivax in the Republic of Korea during 2010-2012 / Malar J 12 : 309 ~
[학술지(정기간행물)] - Lim CS / 2000 / Analysis of Plasmodium vivax merozoite surface protein-1 gene sequences from resurgent Korean isolates / Am J Trop Med Hyg 62 : 261 ~ 265
[학술지(정기간행물)] - Guerra CA / 2007 / Assembling a global database of malaria parasite prevalence for the Malaria Atlas Project / Malar J 6 : 17 ~
[학술지(정기간행물)] - Soh CT / 1985 / Current status of malaria in Korea / Yonsei Rep Trop Med 16 : 11 ~ 18
[학술지(정기간행물)] - Kim TS / 2013 / Decreasing incidence of Plasmodium vivax in the Republic of Korea during 2010-2012 / Malar J 12 : 309 ~
[학술지(정기간행물)] - Lim CS / 2000 / Analysis of Plasmodium vivax merozoite surface protein-1 gene sequences from resurgent Korean isolates / Am J Trop Med Hyg 62 : 261 ~ 265
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