지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.11
- 수록면
- 537 - 546 (10page)
- DOI
- 10.7856/kjcls.2017.28.4.537
이용수
초록· 키워드
오류제보하기
This study was performed to determine the hepatoprotective effects of ethanol extract of loquat leaf (LL) on alcohol-induced liver damage in rats. Sprague-Dawley rats (n=32) were divided into the following four groups: normal group (NOR), ethanol administrated group (ET), ethanol plus LL 200 ㎎/㎏ BW/day administrated group (ET-LLL), and ethanol plus LL 400 ㎎/㎏ Bw/day administrated group (ET-LLH). Body weight gain and food intake of the ET group were significantly reduced compared to those of the ET-LLL and ET-LLH groups. Serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), and lactate dehydrogenase (LDH) activities elevated by ethanol administration were significantly reduced by LL administration. Serum triglyceride (TG) and total cholesterol (TC) contents and hepatic TG and TC contents of the ET group were significantly elevated compared to those of the NOR group. However, TG and TC contents in the serum and liver were significantly reduced in the ET-LLH group. Hepatic glutathione (GSH) contents of the ET-LLL and ET-LLH groups were significantly elevated, and hepatic thiobarbituric acid reactive substances (TBARS) contents were reduced compared to that of the ET group. Taken together, these results suggest that LL may have a possible protective effect on the improvement of hepatic injury by ethanol administration.
목차
ABSTRACT
Ⅰ. 서론
Ⅱ. 연구방법
Ⅲ. 결과 및 고찰
Ⅳ. 요약 및 결론
References
참고문헌 (47)
참고문헌 신청
[학술지(정기간행물)] - Banno N / 2005 / Anti-inflammatory and antitumor promoting effect of the triterpene acid from the leaves of Eriobotrya japonica / Biol Pharm Bull 28 (10) : 1995 ~ 1999
[학술지(정기간행물)] - Bjorntorp P / 1988 / The associations between obesity, adipose tissue distribution and disease / Acta Med Scand 723 (1) : 121 ~ 134
[학술지(정기간행물)] - Bjorntorp P / 1990 / "Portal"adipose tissue as a generator of risk factors for cardiovascular disease and diabetes / Arterioscrosis 10 (4) : 493 ~ 496
[학술지(정기간행물)] - Buege JA / 1978 / The thiobarbituric acid assay / Methods Enzymol 5 (4) : 306 ~ 307
[학술지(정기간행물)] - Biggs HG / 1975 / A manual colorimetric assay of triglyceride in serum / Clin Chem 21 (3) : 437 ~ 441
[학술지(정기간행물)] - Bjorntorp P / 1988 / The associations between obesity, adipose tissue distribution and disease / Acta Med Scand 723 (1) : 121 ~ 134
[학술지(정기간행물)] - Bjorntorp P / 1990 / "Portal"adipose tissue as a generator of risk factors for cardiovascular disease and diabetes / Arterioscrosis 10 (4) : 493 ~ 496
[학술지(정기간행물)] - Buege JA / 1978 / The thiobarbituric acid assay / Methods Enzymol 5 (4) : 306 ~ 307
[학술지(정기간행물)] - Biggs HG / 1975 / A manual colorimetric assay of triglyceride in serum / Clin Chem 21 (3) : 437 ~ 441
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UCI(KEPA) : I410-ECN-0101-2018-590-001582550