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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.12
- 수록면
- 388 - 394 (7page)
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초록· 키워드
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Recently, coffee is the most popular beverage for modern people. A great number of substances are found in coffee beans and have been studied for many years such as aliphatic and aromatic compounds. However, studies on the physiological activity of coffee extracts are insufficient. This study was performed to determine the contents of caffeine and chlorogenic acid in coffee extracts according to the solvent and to investigate the physiological activity of coffee extracts. Coffee extracts were extracted by ultrasonication method with various types of solvents including distilled water, ethanol, and other organic solvents under 50℃ and 80℃. The contents of caffeine and chlorogenic acid in coffee extracts were determined by Liquid Chromatography-Mass Spectrometry (LC-MS). Also, cytotoxic and antioxidative effects of coffee extracts were evaluated with MTT and DPPH assays to analyze the physiological activity. As a result, it was confirmed that caffeine and chlorogenic acid contents were extracted in distilled water with the highest rate. Antioxidative activity was observed below 10-fold dilute of coffee extracts, however cytotoxicity was not observed. In conclusion, distilled water was the best solvent for extracting caffeine and chlorogenic acids from coffee bean with ultrasonication and these coffee extracts are less cytotoxic in human skin cell lines and have antioxidant effect.
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참고문헌 (15)
참고문헌 신청
Ayelign A, Sabally K. Determination of chlorogenic acids (CGA) in coffee beans using HPLC. American Journal of Research Communication. 2013. 1: 78-91.
Campos-Florian J, Bardales-Valdivia J, Caruajulca-Guevara L, Cueva-Llanos D. Anti-diabetic effect of coffea arabica, in alloxan-induced diabetic rats. Emirates Journal of Food and Agriculture. 2013. 25: 772-777.
Cho IH, Hong MS, Lee ES, Kim SJ, Lee YC, Kim SD, Jo HB, Kim JH, Jung K. Study of the characteristics of roasted coffee bean in Seoul. Journal of Food Hygiene and Safety. 2015. 30: 236 -241.
Cho S, Kim OH. Antioxidative activity and protein expression effects of the extracts from cinnamomum camphora on the hair-growth relevant factors. Asian Journal of Beauty Cosmetology. 2016. 14: 18-29.
Farah A, Monteiro M, Donangelo CM, Lafay S. Chlorogenic acids from green coffee extract are highly bioavailable in humans. The Journal of Nutrition. 2008. 138: 2309-2315.
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UCI(KEPA) : I410-ECN-0101-2018-510-001723297