지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.4
- 수록면
- 154 - 159 (6page)
이용수
초록· 키워드
오류제보하기
Background: This study was carried out to investigate the effect of the steaming process on chemical constituents, free radical scavenging activity, and antiproliferative effect of Vietnamese ginseng.
Methods: Samples of powdered Vietnamese ginseng were steamed at 120℃ for various times and their extracts were subjected to chemical and biological studies.
Results: Upon steaming, contents of polar ginsenosides, such as Rb1, Rc, Rd, Re, and Rg1, were rapidly decreased, whereas less polar ginsenosides such as Rg3, Rg5, Rk1, Rk3, and Rh4 were increased as reported previously. However, ocotillol type saponins, which have no glycosyl moiety at the C-20 position, were relatively stable on steaming. The radical scavenging activity was increased continuously up to 20 h of steaming. Similarly, the antiproliferative activity against A549 lung cancer cells was also increased.
Conclusion: It seems that the antiproliferative activity is closely related to the contents of ginsenoside Rg3, Rg5, and Rk1.
Methods: Samples of powdered Vietnamese ginseng were steamed at 120℃ for various times and their extracts were subjected to chemical and biological studies.
Results: Upon steaming, contents of polar ginsenosides, such as Rb1, Rc, Rd, Re, and Rg1, were rapidly decreased, whereas less polar ginsenosides such as Rg3, Rg5, Rk1, Rk3, and Rh4 were increased as reported previously. However, ocotillol type saponins, which have no glycosyl moiety at the C-20 position, were relatively stable on steaming. The radical scavenging activity was increased continuously up to 20 h of steaming. Similarly, the antiproliferative activity against A549 lung cancer cells was also increased.
Conclusion: It seems that the antiproliferative activity is closely related to the contents of ginsenoside Rg3, Rg5, and Rk1.
목차
abstract
1. Introduction
2. Materials and methods
3. Results and discussion
4. Conclusion
References
참고문헌 (24)
참고문헌 신청
1. [학술지(정기간행물)] - Nguyen TN / 1989 / Studyon Panax vietnamensis Haet Grushv., Araliaceace. Botany, tissue culture-chemistry-biological properties / Herbal Polonica 35 : 1 ~ 229
2. [학술지(정기간행물)] - Duc NM / 1993 / Saponins from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. Collected in central Vietnam. I / Chem Pharm Bull 41 : 2010 ~ 2014
3. [학술지(정기간행물)] - Duc NM / 1994 / Saponins from Vietnamese Ginseng, Panax vietnamensis Ha et Grushv. Collected in central Vietnam. II / Chem Pharm Bull 42 : 115 ~ 122
4. [학술지(정기간행물)] - Duc NM / 1994 / Saponins from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. collected in central Vietnam. III / Chem Pharm Bull 42 : 634 ~ 640
5. [학술지(정기간행물)] - Tran LQ / 2001 / Triterpene saponins from Vietnamese ginseng (Panax vietnamensis) and their hepatocytoprotective activity / J Nat Prod 64 : 456 ~ 461
2. [학술지(정기간행물)] - Duc NM / 1993 / Saponins from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. Collected in central Vietnam. I / Chem Pharm Bull 41 : 2010 ~ 2014
3. [학술지(정기간행물)] - Duc NM / 1994 / Saponins from Vietnamese Ginseng, Panax vietnamensis Ha et Grushv. Collected in central Vietnam. II / Chem Pharm Bull 42 : 115 ~ 122
4. [학술지(정기간행물)] - Duc NM / 1994 / Saponins from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. collected in central Vietnam. III / Chem Pharm Bull 42 : 634 ~ 640
5. [학술지(정기간행물)] - Tran LQ / 2001 / Triterpene saponins from Vietnamese ginseng (Panax vietnamensis) and their hepatocytoprotective activity / J Nat Prod 64 : 456 ~ 461
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2018-524-001597277