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Changes of Cognitive Function and Depression following Chemotherapy in Women with Breast Cancer - A Prospective Study -
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유방암 환자의 항암화학요법에 따른 인지기능과 우울 : 전향적 종단 연구

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Type
Academic journal
Author
Oh, Pok Ja (삼육대학교) Lee, Jung Ran (원자력병원) Kim, Hyun Ah (원자력병원)
Journal
Korean Oncology Nursing Society Asian Oncology Nursing Vol.18 No.2 KCI Accredited Journals ESCI
Published
2018.6
Pages
66 - 74 (9page)

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Changes of Cognitive Function and Depression following Chemotherapy in Women with Breast Cancer - A Prospective Study -
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Research history (4)

2018

Changes of Cognitive Function and Depression following Chemotherapy in Women with Breast Cancer - A Prospective Study -
Oh ,  Pok Ja ,  Lee Asian Oncology Nursing 2018.06 Academic journal

2017

Change of Cancer Symptom, Depression and Quality of Life based on Phases of Chemotherapy in Patients with Colorectal or Stomach Cancer : A Prospective Study
Oh ,  Pok Ja ,  Lim Korean Journal of Adult Nursing 2017.06 Academic journal

2016

항암화학요법을 시행한 소화기계 암환자의 인지기능, 피로, 심리적 디스트레스 및 삶의 질의 변화
오복자 ,  이정란 ,  문선미 성인간호학회 학술대회 2016.06 Proceeding

2013

Cognitive Behavioral Therapy for Psychological Distress, Self Care and Quality of Life in Patients with Cancer : A Meta-analysis
Oh ,  Pok Ja ,  Lee Korean Journal of Adult Nursing 2013.08 Academic journal
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Purpose: This study was done to identify the changes of cognitive function and depression following Chemotherapy in women with breast cancer. Methods: Fifty patients participated in the study and completed the questionnaire at three-time points: pre-chemotherapy, post-chemotherapy, and six months after the completion of chemotherapy. The assessment tools were: everyday cognition, the Montreal Cognitive Assessment, and the Hospital Anxiety and Depression Scale. Data were analyzed using descriptive statistics and repeated measures analysis of variance. Results: Immediately after chemotherapy, 52.0% of patients complained of subjective cognitive decline and reported greater difficulty in the cognitive domains of attention, memory, and visuospatial abilities. At six-month follow-up, 24.0% of patients exhibited mild cognitive decline. Repeated measures ANOVA showed a significant decline in cognitive function after chemotherapy. However, improvement was observed 6 months after the completion of chemotherapy. Depression showed similar patterns to cognitive function. Higher cognitive decline scores were significantly correlated with higher depression (r=.33, p=.020). Conclusion: These results suggest that chemotherapy is highly associated with cognitive decline and depression in women with breast cancer. Nursing intervention is needed to relieve depression as well as cognitive decline in patients undergoing chemotherapy.
#Drug Therapy #Depression #Longitudinal Studies #Cognitive Dysfunction

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UCI(KEPA) : I410-ECN-0101-2018-512-003163226