지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.95 No.4
- 발행연도
- 2018.10
- 수록면
- 175 - 182 (8page)
이용수
초록· 키워드
오류제보하기
Purpose: A soft texture of the pancreas is one of the most important predisposing factors for a pancreatic fistula. Thus, in a porcine model, we investigated a method to harden the pancreas locally by directly injecting an artificial material.
Methods: During the laparotomy, 51 samples from 17 pigs, including 13 survival models, were randomly divided into 3 groups and either received a direct injection into the pancreas of MHL (1:4 mixture of histoacryl [n-butyl cyanoacrylate] and lipiodol) (group E) or saline (group C) or only received a pinprick into the pancreas without injecting a substance (sham). We measured the change in the pancreatic hardness after the injection using a durometer and examined the histological change of the pancreas using the fibrosis grade in the survival model.
Results: The postinjection hardness of the pancreas was significantly increased in group E compared to group C and the sham group (P < 0.001). Pathologically, all cases in group E showed a severe fibrotic change, whereas the other groups demonstrated mild to no fibrosis (P < 0.001). The fibrosis in group E was localized to the area of the injection, while the surrounding areas were preserved.
Conclusion: The direct injection of MHL could induce focal hardening and fibrotic changes in the pancreas of the porcine model.
Methods: During the laparotomy, 51 samples from 17 pigs, including 13 survival models, were randomly divided into 3 groups and either received a direct injection into the pancreas of MHL (1:4 mixture of histoacryl [n-butyl cyanoacrylate] and lipiodol) (group E) or saline (group C) or only received a pinprick into the pancreas without injecting a substance (sham). We measured the change in the pancreatic hardness after the injection using a durometer and examined the histological change of the pancreas using the fibrosis grade in the survival model.
Results: The postinjection hardness of the pancreas was significantly increased in group E compared to group C and the sham group (P < 0.001). Pathologically, all cases in group E showed a severe fibrotic change, whereas the other groups demonstrated mild to no fibrosis (P < 0.001). The fibrosis in group E was localized to the area of the injection, while the surrounding areas were preserved.
Conclusion: The direct injection of MHL could induce focal hardening and fibrotic changes in the pancreas of the porcine model.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Issues in pancreatic cancer and need for collaboration in asian pancreas society
Annals of Hepato-Biliary-Pancreatic Surgery
2022 .12
-
Pancreatic Compression during Lymph Node Dissection in Laparoscopic Gastrectomy: Possible Cause of Pancreatic Leakage
Journal of Gastric Cancer
2018 .06
-
Impact of soft pancreas on pancreaticoduodenectomy outcomes and the development of the preoperative soft pancreas risk score
Annals of Hepato-Biliary-Pancreatic Surgery
2025 .02
-
Pancreatic fistula and mortality after surgical management of pancreatic trauma : analysis of 81 consecutive patients during 11 years at a Korean trauma center
Annals of Surgical Treatment and Research
2018 .07
-
Pancreas cancer
대한외과학회 학술대회 초록집
2015 .11
-
The effect of atrophied pancreas as shown in the preoperative imaging on the leakage rate after pancreaticoduodenectomy
Annals of Hepato-Biliary-Pancreatic Surgery
2022 .05
-
Must Know for Pancreas Injury
대한외과학회 학술대회 초록집
2020 .11
-
Are you prepared for pancreas bifidum? A case report
Annals of Surgical Treatment and Research
2018 .01
-
Distribution and Characteristics of Pancreatic Volume Using Computed Tomography Volumetry
Healthcare Informatics Research
2020 .01
-
Distal pancreatectomy for pancreatic arteriovenous malformation : report of a case
Annals of Hepato-Biliary-Pancreatic Surgery
2017 .08
-
18F-FDG PET-CT 검사에서 췌장암, 췌장염, 정상 췌장에 대한 최대표준섭취계수의 임상적 기준 설정
의공학회지
2018 .01
-
The efficacy of 18F-FDG PET/CT in the preoperative evaluation of pancreatic lesions
Annals of Surgical Treatment and Research
2020 .04
-
A Novel Pancreatic Imaging Window for Stabilized Longitudinal In Vivo Observation of Pancreatic Islets in Murine Model
Diabetes and Metabolism Journal
2020 .01
-
Postoperative outcomes of distal pancreatectomy for retroperitoneal sarcoma abutting pancreas in left upper quadrant
대한임상종양학회 학술대회지
2021 .06
-
Pancreatic Cancer
대한외과학회 학술대회 초록집
2021 .11
-
Pancreatic tuberculosis revealed by a pancreatic mass
대한외과학회 학술대회 초록집
2017 .11
-
Pancreas, Hide and Seek
대한외과학회 학술대회 초록집
2022 .11
-
Experience from 100 consecutive pancreas transplants amidst low national transplant activity: a retrospective study at a single center in Korea
Clinical Transplantation and Research
2024 .09
-
Isolated Traumatic Injury of the Pancreatic Head: A Case Report
Journal of trauma and injury : JTI
2016 .01
-
The impact of perioperative inotropes on the incidence of pancreatic leak following pancreaticoduodenectomy
Annals of Hepato-Biliary-Pancreatic Surgery
2019 .11
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2018-514-003583622