지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.96 No.2
- 발행연도
- 2019.2
- 수록면
- 95 - 99 (5page)
이용수
초록· 키워드
오류제보하기
Purpose: Herpes zoster (HZ) is caused by reactivation of the varicella zoster virus, which occurs frequently in liver transplant recipients with impaired cellular immunity. The purpose of this study was to evaluate the incidence and risk factors for HZ after adult liver transplantation (LT).
Methods: In our institution, 993 patients underwent adult LT from January 1997 to December 2013. We retrospectively analyzed the incidence rate of HZ and risk factors for HZ after LT.
Results: Of 993 LT recipients, 101 (10.2%) were diagnosed with HZ. The incidence of HZ at 1, 3, 5, and 10 years was 6.6%, 9.1%, 10.0%, and 11.9%, respectively. Therefore, we observed that the incidence of HZ after LT was 16.3 per 1,000 personyears. Older age (≥50 years) at LT and mycophenolate mofetil (MMF) exposure were independent risk factors of HZ infection after adult LT.
Conclusion: Patients older than 50 years or with MMF exposure are considered to be at high risk for HZ. Therefore, adult liver recipients with such factors should not be given strong immunosuppression treatments.
Methods: In our institution, 993 patients underwent adult LT from January 1997 to December 2013. We retrospectively analyzed the incidence rate of HZ and risk factors for HZ after LT.
Results: Of 993 LT recipients, 101 (10.2%) were diagnosed with HZ. The incidence of HZ at 1, 3, 5, and 10 years was 6.6%, 9.1%, 10.0%, and 11.9%, respectively. Therefore, we observed that the incidence of HZ after LT was 16.3 per 1,000 personyears. Older age (≥50 years) at LT and mycophenolate mofetil (MMF) exposure were independent risk factors of HZ infection after adult LT.
Conclusion: Patients older than 50 years or with MMF exposure are considered to be at high risk for HZ. Therefore, adult liver recipients with such factors should not be given strong immunosuppression treatments.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (17)
참고문헌 신청
Levitsky J / 2005 / Herpes zoster infection after liver transplantation : a case-control study / Liver Transpl 11:320~325
김유정 / 2014 / Population-Based Study of the Epidemiology of Herpes Zoster in Korea / Journal of Korean Medical Science 29(12):1706~1710
Herrero JI / 2004 / Herpes zoster after liver transplantation : incidence, risk factors, and complications / Liver Transpl 10:1140~1143
Hamaguchi Y / 2015 / Incidence and risk factors for herpes zoster in patients undergoing liver transplantation / Transpl Infect Dis 17:671~678
Fishman JA / 2013 / Overview: cytomegalovirus and the herpesviruses in transplantation / Am J Transplant 13(Suppl 3):1~8
김유정 / 2014 / Population-Based Study of the Epidemiology of Herpes Zoster in Korea / Journal of Korean Medical Science 29(12):1706~1710
Herrero JI / 2004 / Herpes zoster after liver transplantation : incidence, risk factors, and complications / Liver Transpl 10:1140~1143
Hamaguchi Y / 2015 / Incidence and risk factors for herpes zoster in patients undergoing liver transplantation / Transpl Infect Dis 17:671~678
Fishman JA / 2013 / Overview: cytomegalovirus and the herpesviruses in transplantation / Am J Transplant 13(Suppl 3):1~8
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UCI(KEPA) : I410-ECN-0101-2019-514-000442122