지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
이용수
초록· 키워드
오류제보하기
Objective: The purpose of this study was to investigate the influence of heritability on the craniofacial soft tissue cephalometric characteristics of monozygotic (MZ) twins, dizygotic (DZ) twins, and their siblings (SIB). Methods: The samples comprised Korean adult twins and their siblings (mean age, 39.8 years; MZ group, n = 36 pairs; DZ group, n = 13 pairs of the same gender; and SIB group, n = 26 pairs of the same gender). Thirty cephalometric variables were measured to characterize facial profile, facial height, soft-tissue thickness, and projection of nose and lip. Falconer’s method was used to calculate heritability (low heritability, h<SUP>2</SUP> < 0.2; high heritability, h<SUP>2</SUP> > 0.9). After principal components analysis (PCA) was performed to extract the models, we calculated the intraclass correlation coefficient (ICC) value and heritability of each component. Results: The MZ group exhibited higher ICC values for all cephalometric variables than DZ and SIB groups. Among cephalometric variables, the highest h<SUP>2</SUP> <SUB>(MZ-DZ)</SUB> and h2 (MZ-SIB) values were observed for the nasolabial angle (NLA, 1.544 and 2.036), chin angle (1.342 and 1.112), soft tissue chin thickness (2.872 and 1.226), and upper lip thickness ratio (1.592 and 1.026). PCA derived eight components with 84.5% of a cumulative explanation. The components that exhibited higher values of h<SUP>2</SUP> <SUB>(MZ-DZ)</SUB> and h2 (MZ-SIB) were PCA2, which includes facial convexity, NLA, and nose projection (1.026 and 0.972), and PCA7, which includes chin angle and soft tissue chin thickness (2.107 and 1.169). Conclusions: The nose and soft tissue chin were more influenced by genetic factors than other soft tissues.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
CONCLUSION
REFERENCES
참고문헌 (28)
참고문헌 신청
Hunter WS / 1965 / A study of the inheritance of craniofacial characteristics as seen in lateral cephalograms of 72 like-sexed twins / Rep Congr Eur Orthod Soc 41:59~70
Nakata N / 1973 / The use of genetic data in the prediction of craniofacial dimensions / Am J Orthod 63:471~480
Nakasima A / 1982 / Hereditary factors in the craniofacial morphology of Angle's Class II and Class III malocclusions / Am J Orthod 82:150~156
Manfredi C / 1997 / Heritability of 39 orthodontic cephalometric parameters on MZ, DZ twins and MN-paired singletons / Am J Orthod Dentofacial Orthop 111:44~51
Savoye I / 1998 / A genetic study of anteroposterior and vertical facial proportions using model-fitting / Angle Orthod 68:467~470
Nakata N / 1973 / The use of genetic data in the prediction of craniofacial dimensions / Am J Orthod 63:471~480
Nakasima A / 1982 / Hereditary factors in the craniofacial morphology of Angle's Class II and Class III malocclusions / Am J Orthod 82:150~156
Manfredi C / 1997 / Heritability of 39 orthodontic cephalometric parameters on MZ, DZ twins and MN-paired singletons / Am J Orthod Dentofacial Orthop 111:44~51
Savoye I / 1998 / A genetic study of anteroposterior and vertical facial proportions using model-fitting / Angle Orthod 68:467~470
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