지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
In this paper, pH-responsive nanocarriers based on mesoporous silica nanoparticles (MSN) modified with the pH-sensitive polymer: poly(N,N-dimethylaminoethyl methacrylate) (PDMAEMA) were constructed, characterized and tested to evaluate their efficacy as drug delivery systems (DDS). The hybrid nanocarriers were synthesized successfully via a simultaneous copolymerization reaction between two monomers; 2-dimethylamino-ethylmethacrylate (DMAEMA) and 3-methacryloxypropyltrimethoxysilane (MPS) within the mesopores of MSN. Exploiting the polymerizable moiety of MPS together with its alkoxysilane moity susceptible to condensation with silanols surface onto silica, MPS comonomer can act as a bridge for yielding a robust and simple hybrid consisting of MSN-P(DMAEMA-co-MPS). In addition, the grafted PDMAEMA serves as efficient gatekeeper to adjust the encapsulation and in vitro release of cargos loaded inside the pores by altering pH values of the medium. These hybrid nanoparticles showed a high loading capacity with quick release in acidic pH, which exists mainly in the diseases environments e.g. inflammatory and cancerous sites.
목차
Abstract
Introduction
Experimental
Results and Discussion
Conclusions
References
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
pH-Responsive Mesoporous Silica Materials for Drug Delivery Application
한국고분자학회 학술대회 연구논문 초록집
2016 .04
-
Synthesis of Mesoporous Silicas Materials for pH-Responsive Drug Delivery
한국고분자학회 학술대회 연구논문 초록집
2015 .10
-
Hydrogels with Anticancer Drug-loaded Mesoporous Silica Nanoparticles (MSNs) for Cancer Therapy
한국고분자학회 학술대회 연구논문 초록집
2018 .04
-
pH-Responsive Poly(acrylic acid) Modified Mesoporous Silica Nanoparticles for Releasing Guest Molecules
한국고분자학회 학술대회 연구논문 초록집
2019 .10
-
pH and reduction triggered poly(histidine) coated mesoporous silica nanoparticles for targeted delivery of curcumin
한국고분자학회 학술대회 연구논문 초록집
2015 .10
-
Preparation of Mesoporous Silicas Modified with Aromatic Functionalities for pH-Responsive Drug Delivery
한국고분자학회 학술대회 연구논문 초록집
2015 .04
-
Cancer-targeted Drug Delivery via Hyaluronic Acid-capped Redox/pH-responsive Hollow Mesoporous Silica Nanoparticles
한국생물공학회 학술대회
2020 .10
-
Redox and pH Responsive Switched Drug Release from Noncovalent Polymer Gatekeeper In Hollow Mesoporous Silica Nanoparticles for Sequential Therapy
한국고분자학회 학술대회 연구논문 초록집
2016 .10
-
MPS 사용자의 특성, 지각된 가치, 만족도간의 관련성 연구
한국컴퓨터정보학회논문지
2023 .04
-
pH-Responsive Polymer-coated Silica–titania Hollow Nanoparticles for Controllable Drug Release
한국고분자학회 학술대회 연구논문 초록집
2020 .10
-
pH-Responsive Mesoporous Materials With Polymer as Gatekeeper
한국고분자학회 학술대회 연구논문 초록집
2017 .04
-
Stimuli-Responsive Mesoporous Silica Nanocarrier with Multifunctional Peptide Gatekeeper for Targeted Drug Delivery
한국고분자학회 학술대회 연구논문 초록집
2016 .04
-
Strategies to Regulate the Degradability of Mesoporous Silica-based Nanoparticles for Biomedical Applications
NANO
2019 .01
-
Stimuli-Responsive Conformational Conversion of Peptide Gatekeepers on the Surface of Mesoporous Silica Nanoparticles for Controlled Drug Delivery
한국고분자학회 학술대회 연구논문 초록집
2018 .04
-
pH-Responsive Polymers for Cancer Drug Delivery
한국고분자학회 학술대회 연구논문 초록집
2015 .04
-
Biodegradable Mesoporous Organosilica Nanoparticle Drug Delivery Platform with Universal Targeting Protein Affibody
한국고분자학회 학술대회 연구논문 초록집
2021 .10
-
pH-responsive drug delivery system based on modified mesoporous materials with polymer as gate keeper
한국고분자학회 학술대회 연구논문 초록집
2017 .04
-
A Redox-responsive drug delivery system based on the functionalized biopolymer coated mesoporous silica nanoparticles
한국고분자학회 학술대회 연구논문 초록집
2015 .10
-
Sequential Drug Release from Hollow Mesoporous Silica Nanoparticle with Non-covalent Polymer Gatekeepers
한국고분자학회 학술대회 연구논문 초록집
2016 .10
-
Effect of Microplastics on the Germination and Growth of Terrestrial Plants
대한환경공학회지
2022 .10
이 논문의 저자 정보
이 논문과 함께 이용한 논문
최근 본 자료
댓글(0)
0