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논문 기본 정보

자료유형
학술저널
저자정보
Md. Jakaria (Konkuk University) Joonsoo Kim (Konkuk University) Govindarajan Karthivashan (Konkuk University) Shin-Young Park (Konkuk University) Palanivel Ganesan (Konkuk University) Dong-Kug Choi (Konkuk University)
저널정보
고려인삼학회 Journal of Ginseng Research Journal of Ginseng Research Vol.43 No.2
발행연도
2019.4
수록면
163 - 171 (9page)

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초록· 키워드

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Common features of neurodegenerative diseases (NDDs) include progressive dysfunctions and neuronal injuries leading to deterioration in normal brain functions. At present, ginseng is one of the most frequently used natural products. Its use has a long history as a cure for various diseases because its extracts and active compounds exhibit several pharmacological properties against several disorders. However, the pathophysiology of NDDs is not fully clear, but researchers have found that various ion channels and specific signaling pathways might have contributed to the disease pathogenesis. Apart from the different pharmacological potentials, ginseng and its active compounds modulate various ion channels and specific molecular signaling pathways related to the nervous system. Here, we discuss the signal modulating potential of ginseng and its active compounds mainly focusing on those relevant to NDDs.

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ABSTRACT
1. Introduction
2. Role of ginseng and its active compounds in modulating ion channel signaling pathways
3. Various specific molecular signaling and their modulating effect by ginseng and its active compounds
4. Conclusion
References

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