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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 165 - 171 (7page)
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초록· 키워드
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An overdose of antihypertensive agents, such calcium channel blockers (CCBs) and angiotensin II receptor blocker (ARBs), and the antihyperglycemic agent, metformin, leads to hypotension and lactic acidosis, respectively. A 40-year-old hypertensive and diabetic man with hyperlipidemia and a weight of 110 kg presented to the emergency room with vomiting, dizziness, and hypotension following an attempted drug overdose suicide with combined CCBs, ARBs, 3-hydroxy-3-methylglutaryl-coemzyme A reductase inhibitors, and metformins. A conventional medical treatment initially administered proved ineffective. The treatment was then changed to simultaneous extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT), which was effective. This shows that simultaneous ECMO and CRRT can be an effective treatment protocol in cases of ineffective conventional medical therapy for hypotension and lactic acidosis due to an overdose of antihypertensive agents and metformin, respectively.
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등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
Abernethy DR / 1999 / Calcium-antagonist drugs / N Engl J Med 341:1447~1457
Tsoi B / 2018 / Comparative Efficacy of Angiotensin II Antagonists in Essential Hypertension : Systematic Review and Network Meta-Analysis of Randomised Controlled Trials / Heart Lung Circ 27:666~682
James PA / 2014 / 2014 evidence-based guideline for the management of high blood pressure in adults : report from the panel members appointed to the Eighth Joint National Committee(JNC 8) / JAMA 311:507~520
Sirtori CR / 1994 / Re-evaluation of a biguanide, metformin:mechanism of action and tolerability / Pharmacol Res 30:187~228
St-Onge M / 2017 / Experts consensus recommendations for the management of calcium channel blocker poisoning in adults / Crit Care Med 45:e306~e315
Tsoi B / 2018 / Comparative Efficacy of Angiotensin II Antagonists in Essential Hypertension : Systematic Review and Network Meta-Analysis of Randomised Controlled Trials / Heart Lung Circ 27:666~682
James PA / 2014 / 2014 evidence-based guideline for the management of high blood pressure in adults : report from the panel members appointed to the Eighth Joint National Committee(JNC 8) / JAMA 311:507~520
Sirtori CR / 1994 / Re-evaluation of a biguanide, metformin:mechanism of action and tolerability / Pharmacol Res 30:187~228
St-Onge M / 2017 / Experts consensus recommendations for the management of calcium channel blocker poisoning in adults / Crit Care Med 45:e306~e315
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