지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 661 - 667 (7page)
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초록· 키워드
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Background/Aims: Seasonal variation may influence the development and exacerbation of inflammatory bowel disease (IBD). However, most epidemiologic studies on this topic have been conducted in Western countries. The purpose of this study was to determine whether birth dates and symptom flares follow a seasonal pattern in Korean patients with IBD.
Methods: Patients with a diagnosis of IBD established between January 2003 and December 2010 were investigated at six university hospitals in Korea. The expected births and flares, with a uniform distribution during the year and considering differences in the number of days in the months of 1year, were calculated. Results: A total of 411 patients with ulcerative colitis (UC) and 316 patients with Crohn disease (CD)were included in the study. Birth during the winter period,and especially in January and February, was associated with an increased risk of IBD, especially in UC patients. The symptom flares of CD patients occurred most frequently in the spring, with a nadir in the autumn. However, no disease flare seasonality was noted for UC patients. Conclusions: Our data suggest that seasonally varying environmental factors during pregnancy and the postpartum period are associated with a susceptibility to IBD later in life and that exacerbations of CD are influenced by seasonal factors.
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참고문헌 (29)
참고문헌 신청
Ahuja V / 2010 / Inflammatory bowel disease in the Asia-Pacific area: a comparison with developed countries and regional differences / J Dig Dis 11 : 134 ~ 147
Angelucci E / 2009 / Monthly and seasonal birth patterns and the occurrence of Crohn’s disease / Am J Gastroenterol 104 : 1608 ~ 1609
Aratari A / 2006 / Seasonal variations in onset of symptoms in Crohn’s disease / Dig Liver Dis 38 : 319 ~ 323
Bai A / 2009 / Seasonality in flares and months of births of patients with ulcerative colitis in a Chinese population / Dig Dis Sci 54 : 1094 ~ 1098
Card TR / 2002 / No seasonality in month of birth of inflammatory bowel disease cases: a prospective population based study of British under 20 year olds / Gut 51 : 814 ~ 81
Angelucci E / 2009 / Monthly and seasonal birth patterns and the occurrence of Crohn’s disease / Am J Gastroenterol 104 : 1608 ~ 1609
Aratari A / 2006 / Seasonal variations in onset of symptoms in Crohn’s disease / Dig Liver Dis 38 : 319 ~ 323
Bai A / 2009 / Seasonality in flares and months of births of patients with ulcerative colitis in a Chinese population / Dig Dis Sci 54 : 1094 ~ 1098
Card TR / 2002 / No seasonality in month of birth of inflammatory bowel disease cases: a prospective population based study of British under 20 year olds / Gut 51 : 814 ~ 81
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