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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 632 - 641 (10page)
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Background/Aims: The efforts to improve biliary plastic stents (PSs) for decreasing biofilm formation and overcome short patency time have been continued. The aim of this study is to evaluate the effect of advanced hydrophilic coating for patency and biodurability of PS. Methods: Using an in vitro bile flow phantom model, we compared patency between prototype PS with hydrophilic coating (PS+HC) and prototype PS without hydrophilic coating (PS-HC). We performed an analysis of the degree of luminal narrowing by microscopic examination. Using an in vivo swine bile duct dilation model made by endoscopic papillary closure and stent insertion, we evaluated biodurability of hydrophilic coating. Results: In the phantom model, PS+HC showed less biofilm formation and luminal narrowing than PS-HC at 8 weeks (p<0.05). A total of 31 stents were inserted into the dilated bile duct of seven swine models, and 24 stents were successfully retrieved 8 weeks later. There was no statistical difference of stent patency between the polyethylene PS+HC and the polyurethane PS+HC. The biodurability of hydrophilic coating was sustained up to 8 weeks, when assessing the coating layer by scanning electron microscopy examination. Conclusions: Advanced hydrophilic coating technology may extend the patency of PS compared to uncoated PS.
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참고문헌 (28)
참고문헌 신청
Raijman I / 2003 / Biliary and pancreatic stents / Gastrointest Endosc Clin N Am 13:561~592
권창일 / 2013 / Functional Self-Expandable Metal Stents in Biliary Obstruction / Clinical Endoscopy 46(5):515~521
Kadakia SC / 1992 / Comparison of 10 French gauge stent with 11.5 French gauge stent in patients with biliary tract diseases / Gastrointest Endosc 38:454~459
van Berkel AM / 1998 / A prospective randomized trial of Teflon versus polyethylene stents for distal malignant biliary obstruction / Endoscopy 30:681~686
England RE / 2000 / A prospective randomised multicentre trial comparing 10 Fr Teflon Tannenbaum stents with 10 Fr polyethylene Cotton-Leung stents in patients with malignant common duct strictures / Gut 46:395~400
권창일 / 2013 / Functional Self-Expandable Metal Stents in Biliary Obstruction / Clinical Endoscopy 46(5):515~521
Kadakia SC / 1992 / Comparison of 10 French gauge stent with 11.5 French gauge stent in patients with biliary tract diseases / Gastrointest Endosc 38:454~459
van Berkel AM / 1998 / A prospective randomized trial of Teflon versus polyethylene stents for distal malignant biliary obstruction / Endoscopy 30:681~686
England RE / 2000 / A prospective randomised multicentre trial comparing 10 Fr Teflon Tannenbaum stents with 10 Fr polyethylene Cotton-Leung stents in patients with malignant common duct strictures / Gut 46:395~400
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