지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 624 - 631 (8page)
이용수
초록· 키워드
오류제보하기
Background/Aims: The diagnosis of spontaneous bacterial peritonitis (SBP) is based on a polymorphonuclear leukocytes (PMNs) exceeding 250/μL in ascitic fluid. The aim of the study was to evaluate serum procalcitonin and ascitic fluid calprotectin as accurate diagnostic markers for detecting SBP. Methods: Seventy-nine patients with cirrhotic ascites were included. They were divided into a SBP group, including 52 patients, and a non-SBP group of 27 patients. Serum procalcitonin, ascitic calprotectin, and serum and ascitic levels of tumor necrosis factor α (TNF-α) and interleukin 6 (IL6) were measured using an enzyme-linked immunosorbent assay. Results: Serum procalcitonin and ascitic calprotectin were significantly higher in SBP patients than in non-SBP patients. Significant increases in both serum and ascitic levels of TNF-α and IL-6 were observed in SBP patients versus nonSBP patients. At a cutoff value of 0.94 ng/mL, serum procalcitonin had 94.3% sensitivity and 91.8% specificity for detecting SBP. In addition, at a cutoff value of 445 ng/mL, ascitic calprotectin had 95.4% sensitivity and 85.2% specificity for detecting SBP. Both were positively correlated with ascitic fluid proteins, PMN count, TNF-α, and IL-6. Conclusions: According to our findings, determination of serum procalcitonin levels and ascitic calprotectin appears to provide satisfactory diagnostic markers for the diagnosis of SBP.
목차
등록된 정보가 없습니다.
참고문헌 (30)
참고문헌 신청
Brann OS / 2001 / Infectious complications of cirrhosis / Curr Gastroenterol Rep 3:285~292
Mousa N / 2014 / Cryptosporidiosis in patients with diarrhea and chronic liver diseases / J Infect Dev Ctries 8:1584~1590
Iqbal J / 2011 / Cyclospora cayetanensis: first report of imported and autochthonous infections in Kuwait / J Infect Dev Ctries 5:383~390
Snelling WJ / 2007 / Cryptosporidiosis in developing countries / J Infect Dev Ctries 1:242~256
Thuluvath PJ / 2001 / Spontaneous bacterial peritonitis:in-hospital mortality, predictors of survival, and health care costs from 1988 to 1998 / Am J Gastroenterol 96:1232~1236
Mousa N / 2014 / Cryptosporidiosis in patients with diarrhea and chronic liver diseases / J Infect Dev Ctries 8:1584~1590
Iqbal J / 2011 / Cyclospora cayetanensis: first report of imported and autochthonous infections in Kuwait / J Infect Dev Ctries 5:383~390
Snelling WJ / 2007 / Cryptosporidiosis in developing countries / J Infect Dev Ctries 1:242~256
Thuluvath PJ / 2001 / Spontaneous bacterial peritonitis:in-hospital mortality, predictors of survival, and health care costs from 1988 to 1998 / Am J Gastroenterol 96:1232~1236
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