Half-Fan-Based Intensity-Weighted Region-of- Interest Imaging for Low-Dose Cone-Beam CT in Image-Guided Radiation Therapy

Boyeol Yoo; Kihong Son; Rizza Pua; 김진성; Alexander Solodov; 조승룡

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자료유형: 학술저널

저자정보: Boyeol Yoo Kihong Son Rizza Pua 김진성 Alexander Solodov 조승룡

저널정보: 대한의료정보학회 Healthcare Informatics Research Healthcare Informatics Research 제22권 제4호

발행연도: 2016.1

수록면: 316 - 325 (10page)

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Objectives: With the increased use of computed tomography (CT) in clinics, dose reduction is the most important feature people seek when considering new CT techniques or applications. We developed an intensity-weighted region-of-interest (IWROI) imaging method in an exact half-fan geometry to reduce the imaging radiation dose to patients in cone-beam CT (CBCT) for image-guided radiation therapy (IGRT). While dose reduction is highly desirable, preserving the high-quality images of the ROI is also important for target localization in IGRT. Methods: An intensity-weighting (IW) filter made of copper was mounted in place of a bowtie filter on the X-ray tube unit of an on-board imager (OBI) system such that the filter can substantially reduce radiation exposure to the outer ROI. In addition to mounting the IW filter, the lead-blade collimation of the OBI was adjusted to produce an exact half-fan scanning geometry for a further reduction of the radiation dose. The chord-based rebinned backprojection-filtration (BPF) algorithm in circular CBCT was implemented for image reconstruction, and a humanoid pelvis phantom was used for the IWROI imaging experiment. Results: The IWROI image of the phantom was successfully reconstructed after beam-quality correction, and it was registered to the reference image within an acceptable level of tolerance. Dosimetric measurements revealed that the dose is reduced by approximately 61% in the inner ROI and by 73% in the outer ROI compared to the conventional bowtie filter-based half-fan scan. Conclusions: The IWROI method substantially reduces the imaging radiation dose and provides reconstructed images with an acceptable level of quality for patient setup and target localization. The proposed half-fan-based IWROI imaging technique can add a valuable option to CBCT in IGRT applications.

#Cone-Beam Computed Tomography #Low-Dose #Region-of-Interest #Half-Fan #Image-Guided Radiation Therapy

참고문헌 (27)

참고문헌 신청

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