지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Proper classification of the causative mechanism of stroke is important for optimizing stroke treatment and assessing prognosis. The primary etiology of stroke differs according to race and ethnicity: emboli originating from the heart or extracranial large arteries are common in Western populations, whereas small-vessel occlusion or intracranial atherosclerosis is more prevalent in Asians. Intracranial atherosclerosis frequently leads to stroke by branch-artery occlusion, and the degree of stenosis in these cases is often <50%. Mild intracranial atherosclerotic stenosis may cause distal embolization, if the atherosclerotic plaque is sufficiently vulnerable. Moreover, high-resolution magnetic resonance imaging studies have identified small plaques causing infarction, even in patients with normal-appearing vascular findings. Such cases, which are prevalent in Asia, could not be classified as large-artery atherosclerosis by previous classification systems. Additionally, single subcortical infarctions, which are usually attributed to lipohyalinotic small-vessel disease, can have other causes, including microatheroma of perforators and atherothrombotic lesions at the parental artery. Single subcortical infarctions associated with parental artery disease or those bordering on the main vessel more often have atherosclerotic characteristics than do those associated with lipohyalinosis of the penetrating artery. In countries where intracranial atherosclerosis is common, such atherosclerotic single subcortical infarctions are predicted to be prevalent. These cases, however, could not be appropriately classified in previous systems. Further effort should be devoted to formulate ischemic stroke classification systems that adequately incorporate results of recent studies and reflect the underling pathologic mechanisms, especially in patients with single subcortical infarction and intracranial atherosclerosis.
목차
등록된 정보가 없습니다.
참고문헌 (60)
참고문헌 신청
Bang OY. / 2002 / Middle cerebral artery stenosis is a major clinical determinant in striatocapsular small, deep infarction / Arch Neurol 59:259~263
Mok VC. / 2003 / Small subcortical infarct and intracranial large artery disease in Chinese / J Neurol Sci 216:55~59
Yoon Y. / 2013 / Single subcortical infarction and atherosclerotic plaques in the middle cerebral artery : high-resolution magnetic resonance imaging findings / Stroke 44:2462~2467
Caplan LR. / 2011 / Stroke classification: A personal view / Stroke 42:S3~S6
Mohr JP. / 1978 / The Harvard Cooperative Stroke Registry : a prospective registry / Neurology 28:754~762
Mok VC. / 2003 / Small subcortical infarct and intracranial large artery disease in Chinese / J Neurol Sci 216:55~59
Yoon Y. / 2013 / Single subcortical infarction and atherosclerotic plaques in the middle cerebral artery : high-resolution magnetic resonance imaging findings / Stroke 44:2462~2467
Caplan LR. / 2011 / Stroke classification: A personal view / Stroke 42:S3~S6
Mohr JP. / 1978 / The Harvard Cooperative Stroke Registry : a prospective registry / Neurology 28:754~762
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