지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Background: Anterior cerebral artery (ACA) can play a great role as a collateral flow to the hypoperfused middle cerebral
artery (MCA) territory. We investigated angiographic findings of the ipsilateral ACA in patients with acute MCA occlusion, and
analyzed the clinical impact of vascular abnormalities of the ACA (VAA). Methods: We retrospectively analyzed the angiographic
findings of the ACA in 29 patients recieved who intra-arterial thrombolysis (IAT) within 6 hours after symptomatic
MCA occlusion. VAA was defined as occlusion or stenosis over 50% presents in any branches of the ACA. Risk factors, serial
National Institutes of Health Stroke Scale (NIHSS) scores, immediate recanalization rates, symptomatic intracranial hemorrhage
(SICH), and modified Rankin Scale (mRS) scores were compared between patients with and without VAA. Results: Eleven
(38%) patients showed VAA (5 occlusions, 6 stenosis). Patients with VAA had a significantly higher baseline median NIHSS
score than patients without (17 vs. 10.5, P<.01). Immediate recanalization rate (55% vs. 67%), occlusion site of MCA, and risk
factors were not different between patients with and without VAA. SICH had a tendency to occur among patients with VAA
(45.5% vs. 16.7%, P=.106). Follow up median NIHSS score at 1 day (16 vs. 8, P<.01), and 7 day (13 vs. 4, P<.01) after
stroke were higher in patients with VAA. Independency rate (mRS ≤2 at 30 day after stroke) was less common in patients
with VAA (18% vs. 61%, P=.029). Conclusion: Occlusion or stenosis of the ACA branches among patients with acute MCA
occlusion is related with severity of stroke and unfavorable outcome after IAT. (Korean Journal of Stroke 2007;9:56-61)
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