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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아소화기영양학회 Pediatric Gastroenterology, Hepatology & Nutrition Pediatric Gastroenterology, Hepatology & Nutrition 제21권 제1호
- 발행연도
- 2018.1
- 수록면
- 20 - 27 (8page)
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초록· 키워드
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Purpose: Minimal change esophagitis (MCE) is a reflux disease without mucosal breaks, known to be partially asso-ciated with abnormal gastric motor function. Electrogastrography (EGG) is commonly applied to assess gastric motor function in a noninvasive fashion. We aimed to determine the relationship between MCE and gastric myoelectrical activity (GME) recorded on EGG in children. Methods: We retrospectively assessed the records of 157 children without underlying disease who underwent both EGG and upper gastrointestinal endoscopy at Gachon University Gil Medical Center between January 2010 and June 2015. The children were stratified according to the appearance of the esophagus (normal vs. MCE). Between-group differences in EGG parameters and their correlation with each MCE finding were statistically analyzed. Results: Only the power ratio, one of the EGG parameters analyzed, differed significantly between the two groups (MCE, 1.68±3.37 vs. normal, 0.76±1.06; p＜0.05), whereas the other parameters, such as dominant frequency, domi-nant power, and the ratio of abnormal rhythm, showed no differences. Among children with MCE, significant correla-tions were noted between erythema and power ratio (p＜0.05), friability and postprandial dominant frequency (p＜0.05), and edema and/or accentuation of mucosal folds and pre-prandial frequency (p＜0.05). Helicobacter pylori infection correlated with postprandial arrhythmia (MCE, 33.59±15.52 vs. normal, 28.10±17.23; p＜0.05). EGG parameters did not differ between children with normal esophagus and those with biopsy-proven chronic esophagitis.Conclusion: In children with MCE, gastric dysmotility may affect the development of MCE, manifesting as EGG abnormalities. H. pylori infection may also affect GME. However, larger prospective investigations are needed to confirm these findings.
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참고문헌 (26)
참고문헌 신청
Vandenplas Y / 2009 / Pediatric gastroesophageal reflux clinical practice guidelines: joint recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) / J Pediatr Gastroenterol Nutr 49:498~547
Onyeador N / 2014 / Paediatric gastroesophageal reflux clinical practice guidelines / Arch Dis Child Educ Pract Ed 99:190~193
Dent J / 2005 / Epidemiology of gastro-oesophageal reflux disease: a systematic review / Gut 54:710~717
Okimoto E / 2015 / Prevalence of gastroesophageal reflux disease in children, adults, and elderly in the same community / J Gastroenterol Hepatol 30:1140~1146
권현정 / 2008 / 복통이 있는 소아청소년에서 식도염의 유병률과 위험인자 / Pediatric Gastroenterology, Hepatology & Nutrition 11(2):103~109
Onyeador N / 2014 / Paediatric gastroesophageal reflux clinical practice guidelines / Arch Dis Child Educ Pract Ed 99:190~193
Dent J / 2005 / Epidemiology of gastro-oesophageal reflux disease: a systematic review / Gut 54:710~717
Okimoto E / 2015 / Prevalence of gastroesophageal reflux disease in children, adults, and elderly in the same community / J Gastroenterol Hepatol 30:1140~1146
권현정 / 2008 / 복통이 있는 소아청소년에서 식도염의 유병률과 위험인자 / Pediatric Gastroenterology, Hepatology & Nutrition 11(2):103~109
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