지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아내분비학회 Annals of Pediatirc Endocrinology & Metabolism Annals of Pediatirc Endocrinology & Metabolism 제19권 제1호
- 발행연도
- 2014.1
- 수록면
- 8 - 12 (5page)
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초록· 키워드
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Severe iodine deficiency causes hypothyroidism that results in impaired somatic growth and motor development in children. Mild and moderate iodine deficiencies cause multifocal autonomous growth of thyroid, which results in thyrotoxicosis. On the other hand, iodine excess is associated with the development of hypothyroidism and thyroid autoimmunity. In areas of iodine deficiency, a sudden increase in iodine intake is associated with transient hyperthyroidism. Recent studies demonstrated that long-term thyroid function of subjects who experienced both iodine deficiency and iodine excess during childhood tended to be abnormal despite optimization of their current iodine intake. Iodine status in the Korean Peninsula is very unique because people in the Republic of Korea have been shown to have predominantly excessive iodine levels, whereas the Democratic People’s Republic of Korea is known to be an iodine-deficient area. Further research is warranted to verify the optimal ranges of iodine intake and to clarify the effects of iodine intake on thyroid disorders in the Korean Peninsula.
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참고문헌 (26)
참고문헌 신청
Andersen S / 2008 / Reliability of studies of iodine intake and recommendations for number of samples in groups and in individuals / Br J Nutr 99 : 813 ~ 818
Bidart JM / 2000 / Expression of pendrin and the Pendred syndrome (PDS)gene in human thyroid tissues / J Clin Endocrinol Metab 85 : 2028 ~ 2033
Burns R / 2011 / The placenta as a compensatory iodine storage organ / Thyroid 21 : 541 ~ 546
De La Vieja A / 2000 / Molecular analysis of the sodium/iodide symporter: impact on thyroid and extrathyroid pathophysiology / Physiol Rev 80 : 1083 ~ 1105
Eskandari S / 1997 / Thyroid Na+/I- symporter. Mechanism, stoichiometry, and specificity / J Biol Chem 272 : 27230 ~ 27238
Bidart JM / 2000 / Expression of pendrin and the Pendred syndrome (PDS)gene in human thyroid tissues / J Clin Endocrinol Metab 85 : 2028 ~ 2033
Burns R / 2011 / The placenta as a compensatory iodine storage organ / Thyroid 21 : 541 ~ 546
De La Vieja A / 2000 / Molecular analysis of the sodium/iodide symporter: impact on thyroid and extrathyroid pathophysiology / Physiol Rev 80 : 1083 ~ 1105
Eskandari S / 1997 / Thyroid Na+/I- symporter. Mechanism, stoichiometry, and specificity / J Biol Chem 272 : 27230 ~ 27238
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