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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 259 - 269 (11page)
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This study has attempted to find out if Plantago asiatica L. seed extract can be used as an ingredient in anti-aging and whitening cosmetics. According to a test on cytotoxicity using B16 melanoma cell, 100.9%, 87.4%, and 81.8% of cell survival rates were observed. Therefore, it has been confirmed that there is no cytotoxicity within the range of concentrations applied. In addition, it appears that it is a safe and effective skin-care material. According to measurement on DPPH radical scavenging activity with a goal of examining the antioxidant activity of the extract, no particular scavenging activity was found at 1㎍/㎖ or 101㎍/㎖. At 100㎍/㎖, on the contrary, 13.1% of antioxidant activity was detected. The ROS of hydrogen peroxide, which is created in the cell, has been measured using DCF-DA fluorescent material. According to observation of the inhibiting effect of ROS, which is created by silica, the creation of ROS has been strongly inhibited from the concentration-dependent aspect. At the highest concentration (100㎍/㎖), 53.8% of antioxidant activity was observed. According to measurement of L-dopa with a goal of figuring out the effect of Plantago asiatica L. seed extract on tyrosinase activity, no particular result was found. According to measurement of tyrosinase activity using B16 melanoma cell, on the contrary, minor inhibition of the activity was detected from a concentration-dependent perspective. At the highest concentration (100㎍/㎖), 15.8% of enzyme activation inhibition rate was observed. Based on the results above, it is likely that Plantago asiatica L. seed extract has a potential to be a natural antioxidant and whitening ingredient in the cosmetic industry. In addition, it could be available for medicinal purposes.
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참고문헌 (28)
참고문헌 신청
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Andreadou I / 2007 / Acute doxorubicin cardiotoxicity is successfully treated with the phytochemical oleuropein through suppression of oxidative and nitrosative stress / J. M
Cho YJ / 1999 / Silica-induced generation of reactive oxygen species in Rat2 fibroblast: role in activation of mitogen-activated protein kinase / Biochemical and biophysical
Furukawa S / 2004 / Increased oxidative stress in obesity and its impact on metabolic syndrome / J Clin Invest 114 : 1752 ~ 1761
Huang HM / 2004 / alpha-keto-beta-methyl-n -valeric acid diminishes reactive oxygen species and alters endoplasmic reticulum Ca2+ stores / Free radical biology & medicin
Andreadou I / 2007 / Acute doxorubicin cardiotoxicity is successfully treated with the phytochemical oleuropein through suppression of oxidative and nitrosative stress / J. M
Cho YJ / 1999 / Silica-induced generation of reactive oxygen species in Rat2 fibroblast: role in activation of mitogen-activated protein kinase / Biochemical and biophysical
Furukawa S / 2004 / Increased oxidative stress in obesity and its impact on metabolic syndrome / J Clin Invest 114 : 1752 ~ 1761
Huang HM / 2004 / alpha-keto-beta-methyl-n -valeric acid diminishes reactive oxygen species and alters endoplasmic reticulum Ca2+ stores / Free radical biology & medicin
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