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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 613 - 618 (6page)
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초록· 키워드
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Two key molecules in skeletal tissues are bone formation master transcription factor Runx2 and the steroid hormone estrogen. It is well known that these two molecules play pivotal roles in bone homeostasis; however, the functional interaction between Runx2 and estrogen synthesis in skeletal tissues is largely unknown. Recent studies have indicated that there is a positive relationship between Runx2 and the estrogen biosynthesis pathway.
In this review, a possible functional link between Runx2and estrogen synthesis pathway in skeletal tissues will be discusses as well as the biological significance of this interaction.
[BMB reports 2011; 44(10): 613-618]
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참고문헌 (22)
참고문헌 신청
Banerjee, C / 1997 / Runt homology domain proteins in osteoblast differentiation: AML3/CBFA1 is a major component of a bone-specific complex / J. Cell. Biochem 66 : 1 ~ 8
Carani, C / 1997 / Effect of testosterone and estradiol in a man with aromatase deficiency / N. Engl. J. Med 337 : 91 ~ 95
Choi, J. Y / 2001 / Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development / Proc. Natl. Acad. Sci. U.S.A
Deladoey, J / 1999 / Aromatase deficiency caused by a novel P450arom gene mutation: impact of absent estrogen production on serum gonadotropin concentration in a boy / J. Cl
Ducy, P / 1997 / Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation / Cell 89 : 747 ~ 754
Carani, C / 1997 / Effect of testosterone and estradiol in a man with aromatase deficiency / N. Engl. J. Med 337 : 91 ~ 95
Choi, J. Y / 2001 / Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development / Proc. Natl. Acad. Sci. U.S.A
Deladoey, J / 1999 / Aromatase deficiency caused by a novel P450arom gene mutation: impact of absent estrogen production on serum gonadotropin concentration in a boy / J. Cl
Ducy, P / 1997 / Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation / Cell 89 : 747 ~ 754
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