지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 293 - 298 (6page)
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초록· 키워드
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The p38 mitogen-activated protein kinase (MAPK) is involved in various processes, including stress responses, development,and differentiation. However, little information on p38 MAPK in insects is available. In this study, a p38 MAPK gene,Accp38b, was isolated from Apis cerana cerana and characterized.
The quantitative real-time PCR (Q-PCR) analysis revealed that Accp38b was induced by multiple stressors.
Notably, the expression of Accp38b was relatively higher in the pupae phase than in other developmental phases. During the pupae phase, Accp38b expression was higher in the thorax than in the head and abdomen and higher in the fat body than in the muscle and midgut. Immunohistochemisty showed significant positive staining of Accp38b in sections from the brain, eyes, fat body, and midgut of A. cerana cerana. These results suggest that Accp38b may play a crucial role in stress responses and have multiple aspects function during development.
[BMB reports 2012; 45(5): 293-298]
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참고문헌 (23)
참고문헌 신청
Adachi-Yamada, T. / 1999 / p38 mitogen-activated protein kinase can be involved in transforming growth factor beta superfamily signal transduction in Drosophila wing morphog
An, H. / 2011 / LZAP inhibits p38 MAPK (p38) phosphorylation and activity by facilitating p38 association with the wild-type p53 induced phosphatase 1 (WIP1) / PLoS One 6 : e
Borders, A. S. / 2008 / The p38α mitogen-activated protein kinase as a central nervous system drug discovery target / BMC Neurosci. 9 (Suppl 2) : S12 ~
Cancino-Rodezno, A. / 2010 / The mitogen-activated protein kinase p38 is involved in insect defense against Cry toxins from Bacillus thuringiensis / Insect. Biochem. Mol. Bi
Carlezon, W. A., Jr. / 2005 / The many faces of CREB / Trends. Neurosci. 28 : 436 ~ 445
An, H. / 2011 / LZAP inhibits p38 MAPK (p38) phosphorylation and activity by facilitating p38 association with the wild-type p53 induced phosphatase 1 (WIP1) / PLoS One 6 : e
Borders, A. S. / 2008 / The p38α mitogen-activated protein kinase as a central nervous system drug discovery target / BMC Neurosci. 9 (Suppl 2) : S12 ~
Cancino-Rodezno, A. / 2010 / The mitogen-activated protein kinase p38 is involved in insect defense against Cry toxins from Bacillus thuringiensis / Insect. Biochem. Mol. Bi
Carlezon, W. A., Jr. / 2005 / The many faces of CREB / Trends. Neurosci. 28 : 436 ~ 445
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