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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 546 - 553 (8page)
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초록· 키워드
오류제보하기
Aging is a natural and gradual process in human life. It is influenced by heredity, environment, lifestyle, and disease. DNA methylation varies with age, and the ability to predict the age of donor using DNA from evidence materials at a crime scene is of considerable value in forensic investigations. Recently, many studies have reported age prediction models based on DNA methylation from various tissues and body fluids. Those models seem to be very promising because of their high prediction accuracies. In this review, the changes of age-associated DNA methylation and the age prediction models for various tissues and body fluids were examined, and then the applicability of the DNA methylation-based age prediction method to the forensic investigations was discussed. This will improve the understandings about DNA methylation markers and their potential to be used as biomarkers in the forensic field, as well as the clinical field.
목차
등록된 정보가 없습니다.
참고문헌 (30)
참고문헌 신청
Alisch RS / 2012 / Ageassociated DNA methylation in pediatric populations / Genome Res 22 : 623 ~ 632
Berdishev MT / 1967 / Nucleotide composition of DNA and RNA from somatic tissues of humpback salmon and its changes during spawning / Biokhimiia 38 : 989 ~ 993
Bird A / 2002 / DNA methylation patterns and epigenetic memory / Genes Dev 16 : 6 ~ 21
Bocklandt S / 2011 / Epigenetic predictor of age / PLoS One 6 : e14821 ~
Fraga MF / 2005 / Epigenetic differences arise during the lifetime of monozygotic twins / Proc Natl Acad Sci U S A 102 : 10604 ~ 10609
Berdishev MT / 1967 / Nucleotide composition of DNA and RNA from somatic tissues of humpback salmon and its changes during spawning / Biokhimiia 38 : 989 ~ 993
Bird A / 2002 / DNA methylation patterns and epigenetic memory / Genes Dev 16 : 6 ~ 21
Bocklandt S / 2011 / Epigenetic predictor of age / PLoS One 6 : e14821 ~
Fraga MF / 2005 / Epigenetic differences arise during the lifetime of monozygotic twins / Proc Natl Acad Sci U S A 102 : 10604 ~ 10609
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