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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 350 - 356 (7page)
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초록· 키워드
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In acquired immunodeficiency syndrome (AIDS) patients, immune reconstitution inflammatory syndrome (IRIS) due to Mycobacterium avium complex (MAC) infection is one of the most difficult IRIS types to manage. We report an unusual case of MAC-associated IRIS. At first the patient was diagnosed human immunodeficiency virus (HIV) infection after he was admitted with pneumocystis pneumonia. After starting antiretroviral therapy he presented unmasked IRIS with MAC infection. Next, he was hospitalized with continuous loose stools and new-onset fever. Investigation included computed tomography (CT), which showed homogeneous enhancement and enlargement of the lymph nodes (LN), elevation of ferritin (>1,650 ng/mL) and lactate dehydrogenase (306 IU/L) levels, and F- fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) scan, which showed increased FDG uptake. These findings were highly indicative of lymphoma. We performed laparoscopic biopsy of the mesenteric LN, and the biopsy culture grew MAC. So we made a diagnosis of MAC-associated. Therefore, IRIS must be considered as a possible diagnosis when AIDS patients develop new symptoms or exhibit exacerbations of existing symptoms. Furthermore the biopsies should be conducted.
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등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Chaisson RE / 1992 / Incidence and natural history of Mycobacterium avium-complex infections in patients with advanced human immunodeficiency virus disease treated with zidovudine. The Zidovudine Epidemiology Study Group / Am Rev Respir Dis 146:285~289
Karakousis PC / 2004 / Mycobacterium avium complex in patients with HIV infection in the era of highly active antiretroviral therapy / Lancet Infect Dis 4:557~565
Phillips P / 2005 / Nontuberculous mycobacterial immune reconstitution syndrome in HIV-infected patients: spectrum of disease and long-term follow-up / Clin Infect Dis 41:1483~1497
Powles T / 2000 / AIDS related systemic non-Hodgkin's lymphoma / Sex Transm Infect 76:335~341
Huhn GD / 2010 / Early development of non-hodgkin lymphoma following initiation of newer class antiretroviral therapy among HIV-infected patients - implications for immune reconstitution / AIDS Res Ther 7:44
Karakousis PC / 2004 / Mycobacterium avium complex in patients with HIV infection in the era of highly active antiretroviral therapy / Lancet Infect Dis 4:557~565
Phillips P / 2005 / Nontuberculous mycobacterial immune reconstitution syndrome in HIV-infected patients: spectrum of disease and long-term follow-up / Clin Infect Dis 41:1483~1497
Powles T / 2000 / AIDS related systemic non-Hodgkin's lymphoma / Sex Transm Infect 76:335~341
Huhn GD / 2010 / Early development of non-hodgkin lymphoma following initiation of newer class antiretroviral therapy among HIV-infected patients - implications for immune reconstitution / AIDS Res Ther 7:44
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