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논문 기본 정보

자료유형
학술저널
저자정보
저널정보
대한중환자의학회 Acute and Critical Care Acute and Critical Care 제27권 제2호
발행연도
2012.1
수록면
94 - 101 (8page)

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Background: Intracranial hemorrhage is a serious disease associated with high mortality and morbidity, and develops suddenly without warning. Although there were known risk factors, it is difficult to prevent brain hemorrhage from critically ill patients in the intensive care unit (ICU). There are several reports that brain hemorrhage, in critically ill patients, occurred in connection with respiratory diseases. The aim of our study is to describe the baseline characteristics and prognosis of patients with intracranial hemorrhage during mechanical ventilation in the ICU. Methods: We retrospectively reviewed the medical records of 56 patients, who developed intracranial hemorrhage in a medical ICU, from May 2008 to December 2011. During the mechanical ventilation in the ICU, patients were implemented with a weaning process, following ACCP (American College of Chest Physicians) criteria. Also, we compared patients with brain hemorrhage to those without brain hemorrhage. Results: Thirty two of the 56 patients (57.1%) were male, and median ages were 63 (17－90) years. The common type of brain hemorrhage confirmed was intracerebral hemorrhage/intraventricular hemorrhage (52.2%). The duration from mechanical ventilation to brain hemorrhage was 6 (0－58) days. Overall hospital mortality was 57.1%, and ICU mortality was 44.6%. The most common cause of death was brain hemorrhage (40.6%). In comparison to patients without brain hemorrhage, study patients showed less use of anticoagulants and lower ventilator pressure. Our study showed that the use of vasopressor, systolic blood pressure, peak airway pressure, and platelet count were associated with brain hemorrhage. Conclusions: Intracranial hemorrhage showed high mortality in critically ill patients with mechanical ventilation. In the future, large case-control study will be needed to evaluate the risk factors of cerebral hemorrhage.
#cerebral hemorrhage #intensive care unit #intracranial hemorrhage #mechanical #ventilators #ventilator weaning.

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참고문헌 (24)

참고문헌 신청
Antithrombotic Trialists' (ATT) Collaboration / 2009 / Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual partici google schola Ariesen MJ / 2003 / Risk factors for intracerebral hemorrhage in the general population: a systematic review / Stroke 34 : 2060 ~ 2065 google schola Bamford J / 1990 / A prospective study of acute cerebrovascular disease in the community: the Oxfordshire Community Stroke Project--1981-86. 2. Incidence, case fatality rates google schola Bilotta F / 2008 / Endotracheal lidocaine in preventing endotracheal suctioning-induced changes in cerebral hemodynamics in patients with severe head trauma / Neurocrit Care google schola Cervera A / 2012 / Ora google schola

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