지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Persistent bone marrow aplasia after intensive chemotherapy is uncommon, but is one of the fatal complications in patients withacute myeloid leukemia (AML). Although allogeneic hematopoietic stem cell transplantation (HSCT) is considered to becontraindicated for patients who have hematologic diseases with serious infections, such as bacterial septicemia or invasive fungaldiseases, combined with prolonged neutropenia due to frequent morbidity and mortality, such risks can be overcome bynon-myeloablative conditioning and best supportive care. Here, we report an AML patient with persistent marrow aplasia afterinduction therapy, treated successfully with reduced-intensity allogeneic HSCT despite severe bacterial and fungal infections.
목차
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참고문헌 (10)
참고문헌 신청
Anderson JE / 1997 / Stem cell transplantation for secondary acute myeloid leukemia: evaluation of transplantation as initial therapy or following induction chemotherapy / Bl
Berman E / 1991 / Results of a randomized trial comparing idarubicin and cytosine arabinoside with daunorubicin and cytosine arabinoside in adult patients with newly diagnose
Hambach L / 2002 / Persistent aplasia after chemotherapy for acute myeloid leukaemia treated with stem cell transplantation from a matched unrelated donor after dose-reduced
Herbrecht R / 2002 / Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis / N Engl J Med 347 : 408 ~ 415
Maertens J / 2004 / Efficacy and safety of caspofungin for treatment of invasive aspergillosis in patients refractory to or intolerant of conventional antifungal therapy / Cl
Berman E / 1991 / Results of a randomized trial comparing idarubicin and cytosine arabinoside with daunorubicin and cytosine arabinoside in adult patients with newly diagnose
Hambach L / 2002 / Persistent aplasia after chemotherapy for acute myeloid leukaemia treated with stem cell transplantation from a matched unrelated donor after dose-reduced
Herbrecht R / 2002 / Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis / N Engl J Med 347 : 408 ~ 415
Maertens J / 2004 / Efficacy and safety of caspofungin for treatment of invasive aspergillosis in patients refractory to or intolerant of conventional antifungal therapy / Cl
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