지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Lung cancer is not only the most common cancer of the elderly but is also the leading cause of cancer-related mortality in Korea.
Therefore, the elderly form a large subgroup of patients with advanced lung cancer. Aging is associated with co-morbidities, poorperformance status, and impaired organ function. These problems can cause uncertainty when selecting the optimal treatment foradvanced lung cancer, and some elderly patients could be undertreated. Patients with non-squamous histology lung cancer, regardlessof age or performance status, should be tested for epidermal growth factor receptor (EGFR) mutations; patients with EGFR mutationssuch as del 19 or L858R are able to receive EGFR tyrosine kinase inhibitors. The treatment options for elderly patients withlung cancer include best supportive care, single agent chemotherapy, platinum-based doublet chemotherapy, and targeted therapy.
The optimum therapeutic option for elderly individuals with advanced lung cancer must be selected carefully, taking into accountboth the risks and benefits.
목차
등록된 정보가 없습니다.
참고문헌 (18)
참고문헌 신청
/ 1999 / Effects of vinorelbine on quality of life and survival of elderly patients with advanced non-small-cell lung cancer. The Elderly Lung Cancer Vinorelbine Italian Stud
Al-Saleh K / 2012 / Role of pemetrexed in advanced non-small-cell lung cancer: meta-analysis of randomized controlled trials, with histology subgroup analysis / Curr Oncol 1
Gridelli C / 2003 / Chemotherapy for elderly patients with advanced non-small-cell lung cancer: the Multicenter Italian Lung Cancer in the Elderly Study (MILES) phase III ra
Hensing TA / 2003 / The impact of age on toxicity, response rate, quality of life, and survival in patients with advanced, Stage IIIB or IV nonsmall cell lung carcinoma trea
Kubota K / 1997 / Cisplatin-based combination chemotherapy for elderly patients with nonsmall- cell lung cancer / Cancer Chemother Pharmacol 40 : 469 ~ 474
Al-Saleh K / 2012 / Role of pemetrexed in advanced non-small-cell lung cancer: meta-analysis of randomized controlled trials, with histology subgroup analysis / Curr Oncol 1
Gridelli C / 2003 / Chemotherapy for elderly patients with advanced non-small-cell lung cancer: the Multicenter Italian Lung Cancer in the Elderly Study (MILES) phase III ra
Hensing TA / 2003 / The impact of age on toxicity, response rate, quality of life, and survival in patients with advanced, Stage IIIB or IV nonsmall cell lung carcinoma trea
Kubota K / 1997 / Cisplatin-based combination chemotherapy for elderly patients with nonsmall- cell lung cancer / Cancer Chemother Pharmacol 40 : 469 ~ 474
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