지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Emphysema is a category of chronic obstructive pulmonary disease characterized by chronic airflow limitation and hyperinflation.
Several decades ago, it was found that the surgical resection of emphysematous lung improved lung function and the long-termsurvival in patients with severe advanced emphysema. However, it was associated with substantial postoperative morbidity, such aspersistent air-leak and mortality. Therefore, bronchoscopic lung volume reduction (BLVR) techniques have been developed toavoid these risks associated with surgery. Of these, endobronchial valves have been subject to the largest number of clinical trials.
Endobronchial valves are unidirectional valves placed in the bronchus of the most hyperinflated lobe to block regional inflation,while allowing exhalation, leading to atelectasis of the target lobe. BLVR using endobronchial valves improves lung function,exercise tolerance, and symptoms. To obtain the maximum clinical benefits, it is important to select patients who have a completelobar fissure and heterogeneous emphysematous lung involvement. Other bronchoscopic approaches are being developed toovercome these limitations.
목차
등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
Brantigan OC / 2009 / The surgical approach to pulmonary emphysema: 1961 / Chest 136 (5) : e30 ~
Cooper JD / 1996 / Results of 150 consecutive bilateral lung volume reduction procedures in patients with severe emphysema / J Thorac Cardiovasc Surg 112 : 1319 ~ 1329
Fishman A / 2003 / A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema / N Engl J Med 348 : 2059 ~ 2073
Herth FJ / 2010 / Endoscopic lung volume reduction / Respiration 79 : 5 ~ 13
Herth FJ / 2012 / Efficacy predictors of lung volume reduction with Zephyr valves in a European cohort / Eur Respir J 39 : 1334 ~ 1342
Cooper JD / 1996 / Results of 150 consecutive bilateral lung volume reduction procedures in patients with severe emphysema / J Thorac Cardiovasc Surg 112 : 1319 ~ 1329
Fishman A / 2003 / A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema / N Engl J Med 348 : 2059 ~ 2073
Herth FJ / 2010 / Endoscopic lung volume reduction / Respiration 79 : 5 ~ 13
Herth FJ / 2012 / Efficacy predictors of lung volume reduction with Zephyr valves in a European cohort / Eur Respir J 39 : 1334 ~ 1342
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