지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Diagnosing hypercalcemia is often challenging because a wide spectrum of diseases-such as malignancy, granulomatous disease,and primary hyperparathyroidism-should be considered. Sarcoidosis is a rare cause of hypercalcemia. The case of a 77-year-oldmale presenting with sarcoidosis-associated hypercalcemia whose serum 1,25(OH)2D level was normal is reported here. Despite anormal 1,25(OH)2D level and minimally enlarged hilar lymphadenopathy, the serum angiotensin-converting enzyme (ACE) levelwas increased. Mediastinoscopic biopsy of the right lower paratracheal lymph node revealed pathological findings compatible withsarcoidosis. Treatment with 30 mg/day oral prednisone was started. Currently, the patient is being treated with a tapered dose of oralprednisone and small doses of vitamin D and calcium. Despite its low incidence, sarcoidosis should be considered a cause ofhypercalcemia. The important diagnostic factors are not only serum calcitriol levels but also serum ACE levels and pathologicalfindings.
목차
등록된 정보가 없습니다.
참고문헌 (10)
참고문헌 신청
Adams JS / 1983 / Metabolism of 25-hydroxyvitamin D3 by cultured pulmonary alveolar macrophages in sarcoidosis / J Clin Invest 72 : 1856 ~ 1860
Adams JS / 1985 / Characterization of 1 alpha-hydroxylation of vitamin D3 sterols by cultured alveolar macrophages from patients with sarcoidosis / J Exp Med 161 : 755 ~ 765
Baughman RP / 2013 / Calcium and vitamin D metabolism in sarcoidosis / Sarcoidosis Vasc Diffuse Lung Dis 30 : 113 ~ 120
Bell NH / 1979 / Evidence that increased circulating 1 alpha, 25-dihydroxyvitamin D is the probable cause for abnormal calcium metabolism in sarcoidosis / J Clin Invest 64 :
Falk S / 2007 / Hypercalcemia as a result of sarcoidosis with normal serum concentrations of vitamin D / Med Sci Monit 13 : CS133 ~ CS136
Adams JS / 1985 / Characterization of 1 alpha-hydroxylation of vitamin D3 sterols by cultured alveolar macrophages from patients with sarcoidosis / J Exp Med 161 : 755 ~ 765
Baughman RP / 2013 / Calcium and vitamin D metabolism in sarcoidosis / Sarcoidosis Vasc Diffuse Lung Dis 30 : 113 ~ 120
Bell NH / 1979 / Evidence that increased circulating 1 alpha, 25-dihydroxyvitamin D is the probable cause for abnormal calcium metabolism in sarcoidosis / J Clin Invest 64 :
Falk S / 2007 / Hypercalcemia as a result of sarcoidosis with normal serum concentrations of vitamin D / Med Sci Monit 13 : CS133 ~ CS136
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