개인구독
소속 기관이 없으신 경우, 개인 정기구독을 하시면 저렴하게
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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Sepsis is a systemic, deleterious host response to infection. The term “severe sepsis” is used when sepsis is complicated by acuteorgan dysfunction, and "septic shock" as sepsis complicated by either hypotension that is refractory to fluid resuscitation or byhyperlactatemia. The number of cases with severe sepsis exceeds 750,000 per year in the United States and the mortality is nowcloser to 20 to 30% in these days. The principles of the initial management bundle are to provide sufficient hemodynamicresuscitation and early initiation of appropriate antibiotics to mitigate uncontrolled infection. Initial resuscitation requires the use ofintravenous fluids and vasopressors. It is very important to achieve the target of initial resuscitation. The supportive cares in ICU arealso significant such as blood component transfusion, glucose control, renal replacement therapy, deep vein thrombosis prophylaxisand stress ulcer prophylaxis. The goals of care and prognosis including end-of-life care should be discussed with patients andfamilies as early as feasible.
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참고문헌 (23)
참고문헌 신청
Angus DC / 2001 / Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care / Crit Care Med 29 : 1303 ~ 1310
Angus DC / 2013 / Severe sepsis and septic shock / N Engl J Med 369 : 840 ~ 851
Annane D / 2013 / Effects of fluid resuscitation with colloids vs crystalloids on mortality in critically ill patients presenting with hypovolemic shock: the CRISTAL randomi
Barie PS / 2005 / Influence of antibiotic therapy on mortality of critical surgical illness caused or complicated by infection / Surg Infect (Larchmt) 6 : 41 ~ 54
Bendjelid K / 2003 / Fluid responsiveness in mechanically ventilated patients: a review of indices used in intensive care / Intensive Care Med 29 : 352 ~ 360
Angus DC / 2013 / Severe sepsis and septic shock / N Engl J Med 369 : 840 ~ 851
Annane D / 2013 / Effects of fluid resuscitation with colloids vs crystalloids on mortality in critically ill patients presenting with hypovolemic shock: the CRISTAL randomi
Barie PS / 2005 / Influence of antibiotic therapy on mortality of critical surgical illness caused or complicated by infection / Surg Infect (Larchmt) 6 : 41 ~ 54
Bendjelid K / 2003 / Fluid responsiveness in mechanically ventilated patients: a review of indices used in intensive care / Intensive Care Med 29 : 352 ~ 360
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