지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한병리학회 Journal of Pathology and Translational Medicine Journal of Pathology and Translational Medicine 제48권 제4호
- 발행연도
- 2014.1
- 수록면
- 292 - 296 (5page)
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초록· 키워드
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Pigmented extramammary Paget’s disease (PEMPD) is an uncommon intraepithelial adenocarcinoma and a rare variant of Paget’s disease affecting skin that is rich in apocrine sweat glands such as the axilla, perianal region and vulva. It most commonly occurs in postmenopausal women and presents as a superficial pigmented scaly macule, mimicking a melanocytic lesion. The histological presentation is adenocarcinoma in situ with an increased number of melanocytes scattered between the Paget’s cells. Therefore, PEMPD may be misdiagnosed as a melanocytic tumour both clinically and histologically. The tumour cells are usually positive for cytokeratin 7, epithelial membrane antigen, Cam 5.2, HER2, and mucicarmine stain while S100 and human melanoma black-45 highlight the processes of reactive dendritic cells. The association between Paget’s cells and intratumoural reactive melanocytes is still unclear. We report our first case of PEMPD associated with an intradermal naevus involving the axilla in a 63-year-old woman.
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참고문헌 (20)
참고문헌 신청
Azzopardi JG / 1977 / Melanocyte colonization and pigmentation of breast carcinoma / Histopathology 1 : 21 ~ 30
Chiba H / 2000 / Two cases of vulval pigmented extramammary Paget’s disease: histochemical and immunohistochemical studies / Br J Dermatol 142 : 1190 ~ 1194
Chiu CS / 2011 / Extramammary Paget’s disease of the unilateral axilla: a review of seven cases in a 20-year experience / Int J Dermatol 50 : 157 ~ 160
Crocker HR / 1889 / Paget’s disease affecting the scrotum and penis / Trans Pathol Soc Lond 40 : 187 ~ 191
Culberson JD / 1956 / Paget’s disease of the nipple: review of twenty-five cases with special reference to melanin pigmentation of Paget cells / AMA Arch Surg 72 : 224 ~ 23
Chiba H / 2000 / Two cases of vulval pigmented extramammary Paget’s disease: histochemical and immunohistochemical studies / Br J Dermatol 142 : 1190 ~ 1194
Chiu CS / 2011 / Extramammary Paget’s disease of the unilateral axilla: a review of seven cases in a 20-year experience / Int J Dermatol 50 : 157 ~ 160
Crocker HR / 1889 / Paget’s disease affecting the scrotum and penis / Trans Pathol Soc Lond 40 : 187 ~ 191
Culberson JD / 1956 / Paget’s disease of the nipple: review of twenty-five cases with special reference to melanin pigmentation of Paget cells / AMA Arch Surg 72 : 224 ~ 23
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