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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한병리학회 Journal of Pathology and Translational Medicine Journal of Pathology and Translational Medicine 제49권 제1호
- 발행연도
- 2015.1
- 수록면
- 5 - 12 (8page)
이용수
초록· 키워드
오류제보하기
Clinical imaging creates visual representations of the body interior for disease assessment. The role of clinical imaging significantly overlaps with that of pathology, and diagnostic workflows largely depend on both fields. The field of clinical imaging is presently undergoing a radical change through the emergence of a new field called molecular imaging. This new technology, which lies at the intersection between imaging and molecular biology, enables noninvasive visualization of biochemical processes at the molecular level within living bodies. Molecular imaging differs from traditional anatomical imaging in that biomarkers known as imaging probes are used to visualize target molecules-of-interest. This ability opens up exciting new possibilities for applications in oncologic, neurological and cardiovascular diseases. Molecular imaging is expected to make major contributions to personalized medicine by allowing earlier diagnosis and predicting treatment response. The technique is also making a huge impact on pharmaceutical development by optimizing preclinical and clinical tests for new drug candidates. This review will describe the basic principles of molecular imaging and will briefly touch on three examples (from an immense list of new techniques) that may contribute to personalized medicine: receptor imaging, angiogenesis imaging, and apoptosis imaging.
목차
등록된 정보가 없습니다.
참고문헌 (21)
참고문헌 신청
Allen AM / 2012 / Assessment of response of brain metastases to radiotherapy by PET imaging of apoptosis with 18F-ML-10 / Eur J Nucl Med Mol Imaging 39 : 1400 ~ 1408
Choe YS / 2007 / Targeted in vivo imaging of angiogenesis: present status and perspectives / Curr Pharm Des 13 : 17 ~ 31
Gore JC / 2011 / Magnetic resonance in the era of molecular imaging of cancer / Magn Reson Imaging 29 : 587 ~ 600
Hamburg MA / 2010 / The path to personalized medicine / N Engl J Med 363 : 301 ~ 304
Hellebust A / 2012 / Advances in molecular imaging : targeted optical contrast agents for cancer diagnostics / Nanomedicine (Lond) 7 : 429 ~ 445
Choe YS / 2007 / Targeted in vivo imaging of angiogenesis: present status and perspectives / Curr Pharm Des 13 : 17 ~ 31
Gore JC / 2011 / Magnetic resonance in the era of molecular imaging of cancer / Magn Reson Imaging 29 : 587 ~ 600
Hamburg MA / 2010 / The path to personalized medicine / N Engl J Med 363 : 301 ~ 304
Hellebust A / 2012 / Advances in molecular imaging : targeted optical contrast agents for cancer diagnostics / Nanomedicine (Lond) 7 : 429 ~ 445
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