지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 170 - 176 (7page)
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초록· 키워드
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Background and Purpose Not only clinical factors, including the CHADS2 score, but also echocardiographic findings have been reported to be useful for predicting the risk of ischemic stroke in patients with nonvalvular atrial fibrillation (NVAF). However, it remains to be determined which of these factors might be more relevant for evaluation of the risk of stroke in each patient.
Methods In 490 patients with NVAF who underwent transesophageal echocardiography (TEE),we examined the long-term incidence of ischemic stroke events (mean follow-up time, 5.7±3.3years). For each patient, the predictive values of gender, the CHADS2 risk factors (congestive heart failure, hypertension, age =75 years, diabetes mellitus, history of cerebral ischemia), the CHADS2score, and the findings on echocardiography, including TEE risk markers, were assessed.
Results The ischemic stroke rate was significantly correlated with the CHADS2 score (p<0.05).
According to the results of univariate analyses, age =75 years, history of cerebral ischemia, CHADS2score =2, and presence of TEE risk were significantly correlated with the incidence of ischemic stroke. Cox proportional hazards regression analyses identified age =75 years and presence of TEE risk as significant predictors of subsequent ischemic stroke events in patients with NVAF.
As compared with that in persons below 75 years of age without TEE risk, the ischemic stroke rate was significantly higher in persons who were =75 years of age with TEE risk (4.3 vs. 0.56%/year,adjusted hazard ratio=8.94, p<0.001).
Conclusions TEE findings might be more relevant predictors of ischemic stroke than the CHADS2score in patients with NVAF. The stroke risk was more than 8-fold higher in patients aged =75 years with TEE risk.
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등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
/ 1996 / Stroke Prevention in Atrial Fibrillation Investigators Committee on Echocardiography. Transesophageal echocardiography in atrial fibrillation: standards for acquisit
/ 1998 / Stroke Prevention in Atrial Fibrillation Investigators Committee on Echocardiography. Transesophageal echocardiographic correlates of thromboembolism in high-risk pa
Dougu N / 2008 / Differential diagnosis of cerebral infarction using an algorithm combining atrial fibrillation and D-dimer level / Eur J Neurol 15 : 295 ~ 300
European Heart Rhythm Association; European Association for Cardio-Thoracic Surgery / 2010 / Guidelines for the management of atrial fibrillation: the Task Force for the Man
Fatkin D / 1994 / Relations between left atrial appendage blood flow velocity, spontaneous echocardiographic contrast and thromboembolic risk in vivo / J Am Coll Cardiol 23 :
/ 1998 / Stroke Prevention in Atrial Fibrillation Investigators Committee on Echocardiography. Transesophageal echocardiographic correlates of thromboembolism in high-risk pa
Dougu N / 2008 / Differential diagnosis of cerebral infarction using an algorithm combining atrial fibrillation and D-dimer level / Eur J Neurol 15 : 295 ~ 300
European Heart Rhythm Association; European Association for Cardio-Thoracic Surgery / 2010 / Guidelines for the management of atrial fibrillation: the Task Force for the Man
Fatkin D / 1994 / Relations between left atrial appendage blood flow velocity, spontaneous echocardiographic contrast and thromboembolic risk in vivo / J Am Coll Cardiol 23 :
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