지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
이용수
초록· 키워드
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Objectives The purpose of this study was to suggest recommendations of antidepressant efficacy compared with placebo, difference in efficacy of antidepressants, and appropriate time of efficacy judgment in antidepressant therapy.
Methods Using recommendations from 12 international and domestic clinical practice guidelines for depression, drawing of recommendation drafts, and peer review, the executive committee developed the guideline.
Results Tricyclic antidepressants (TCAs), monoamine oxidase inhibitors (MAOI), selective serotonin reuptake inhibitors (SSRI), serotonin and norepinephrine reuptake inhibitors (SNRIs), norepinephrine and specific serotonergic antidepressants (NaSSAs), norepinephrine and dopamine reuptake inhibitors (NDRIs), and serotonin antagonist and reuptake inhibitors (SARIs) were strongly recommended as having antidepressant efficacy compared with placebo. Difference in efficacy of antidepressants was as follows. TCAs, MAOI, SSRI, SNRIs, and NaSSAs were strongly recommended, however, NDRIs, SARIs were weakly recommended. If there was no or minimal improvement with treatment, appropriate time of efficacy judgment in antidepressant therapy was estimated to be after two to four weeks.
Conclusion We hope that the results of this study will be helpful in encouraging the optimal treatment by understanding antidepressant efficacy compared with placebo, difference in efficacy of antidepressants, and appropriate time of efficacy judgment in antidepressant therapy.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Arroll B / 2005 / Efficacy and tolerability of tricyclic antidepressants and SSRIs compared with placebo for treatment of depression in primary care: a meta-analysis / The Annals of F
Bech P / 2000 / Meta-analysis of randomised controlled trials of fluoxetine v. placebo and tricyclic antidepressants in the short-term treatment of major depression : 421 ~ 428
Chun TH / 2008 / The asthma/mental health nexus in a population-based sample of the United States / CHEST Journal 134 : 1176 ~ 1182
Cipriani A / 2005 / Fluoxetine versus other types of pharmacotherapy for depression / Cochrane Database
Cleland JA / 2007 / Associations of depression and anxiety with gender, age, health-related quality of life and symptoms in primary care COPD patients / Family Practice 24 :
Bech P / 2000 / Meta-analysis of randomised controlled trials of fluoxetine v. placebo and tricyclic antidepressants in the short-term treatment of major depression : 421 ~ 428
Chun TH / 2008 / The asthma/mental health nexus in a population-based sample of the United States / CHEST Journal 134 : 1176 ~ 1182
Cipriani A / 2005 / Fluoxetine versus other types of pharmacotherapy for depression / Cochrane Database
Cleland JA / 2007 / Associations of depression and anxiety with gender, age, health-related quality of life and symptoms in primary care COPD patients / Family Practice 24 :
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