지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 446 - 453 (8page)
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초록· 키워드
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Objective We investigated demographic influences on Korean version of Disability Assessment for Dementia (DAD-K) performance and developed normative data for DAD-K.
Methods The DAD-K was administered to 2362 normal controls (NCs), 296 patients with mild cognitive impairment (MCI) and 293 patients with Alzheimer’s disease (AD). MANOVA and ROC curve analysis were used to compare DAD-K performance and the diagnostic accuracy of DAD-K, respectively. The demographic influence on DAD-K scores was analyzed by multiple linear regression and ANOVA. Normative DAD-K data were calculated using natural logarithmic transformation.
Results All DAD-K scores were significantly different among groups (p<0.001). Post hoc analysis showed that instrumental activities of daily living (IADL), executive function and DAD-K total scores began to decline significantly in the very mild stage of AD, whereas the basic activities of daily living (BADL) scores began to decline in the mild stage of AD. The area under the ROC curve differentiating MCI or AD from NC was 0.737 and that differentiating AD from MCI or NC was 0.911. IADL and planning and organization scores were influenced by age and education and performance and DAD-K total scores were influenced by education.
Conclusion The demographic influences on DAD-K scores are not conspicuous and are mainly limited to the IADL and planning and organization scores. Unitary or minimally stratified norms for a specific population were developed for DAD-K application. Our results suggest that the DAD-K is useful for differentiating NC or MCI from AD but not as powerful for differentiating NC from MCI.
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참고문헌 (23)
참고문헌 신청
Bahia VS / 2010 / Functional disability in Alzheimer disease: a validation study of the Brazilian version of the Disability Assessment for Dementia (DAD-Br) / Alzheimer Dis
Barberger-Gateau P / 1999 / Functional impairment in instrumental activities of daily living: an early clinical sign of dementia? / J Am Geriatr Soc 47 : 456 ~ 462
Brown PJ / 2011 / Functional impairment in elderly patients with mild cognitive impairment and mild Alzheimer disease / Arch Gen Psychiatry 68 : 617 ~ 626
De Vreese LP / 2008 / Functional disability in early Alzheimer’s disease - a validation study of the Italian version of the disability assessment for dementia scale / Demen
Fisk JD / 2003 / Variations in case definition affect prevalence but not outcomes of mild cognitive impairment / Neurology 61 : 1179 ~ 1184
Barberger-Gateau P / 1999 / Functional impairment in instrumental activities of daily living: an early clinical sign of dementia? / J Am Geriatr Soc 47 : 456 ~ 462
Brown PJ / 2011 / Functional impairment in elderly patients with mild cognitive impairment and mild Alzheimer disease / Arch Gen Psychiatry 68 : 617 ~ 626
De Vreese LP / 2008 / Functional disability in early Alzheimer’s disease - a validation study of the Italian version of the disability assessment for dementia scale / Demen
Fisk JD / 2003 / Variations in case definition affect prevalence but not outcomes of mild cognitive impairment / Neurology 61 : 1179 ~ 1184
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