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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 90 - 93 (4page)
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초록· 키워드
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We aimed to assess the effectiveness and safety of clonidine extended release (ER) treatment in Korean youth with ADHD and/or Tourette’s disorder. We retrospectively reviewed the medical records of 29 children and adolescents treated with clonidine ER. The effectiveness were retrospectively measured at baseline and after 4 and 12 weeks based on the Clinical Global Impression-Severity (CGI-S) and Clinical Global Impression-Improvement (CGI-I) scores. Safety was evaluated at each visit based on spontaneous reports from the subjects or from their parents/guardians. Significant decreases in the CGI-S scores for both ADHD (F=23.478, p<0.001, partial η2=0.540) and tic symptoms (F=15.137, p<0.001, partial η2=0.443) were noted over 12 weeks. The most common adverse event was somnolence (n=9, 31.0%) and life-threatening adverse effects were not observed. Our results provide preliminary evidence for the effectiveness and safety of clonidine ER.
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등록된 정보가 없습니다.
참고문헌 (10)
참고문헌 신청
Hirota T / 2014 / Alpha-2 agonists for attention-deficit/hyperactivity disorder in youth: a systematic review and metaanalysis of monotherapy and add-on trials to stimulant therapy / J Am Acad Child Adolesc Psychiatry 53:153~173
Schwartz S / 2014 / Efficacy and safety of atomoxetine in children and adolescents with attention-deficit/hyperactivity disorder: results from a comprehensive meta-analysis and metaregression / J Am Acad Child Adolesc Psychiatry 53:174~187
Faraone SV / 2009 / Using Meta-analysis to compare the efficacy of medications for attention-deficit/hyperactivity disorder in youths / P T 34:678~694
Ganos C / 2015 / Tics and tourette syndrome / Neurol Clin 33:115~136
Jiao F / 2016 / Clinical observation on treatment of Tourette syndrome in Chinese children by clonidine adhesive patch / Eur J Paediatr Neurol 20:80~84
Schwartz S / 2014 / Efficacy and safety of atomoxetine in children and adolescents with attention-deficit/hyperactivity disorder: results from a comprehensive meta-analysis and metaregression / J Am Acad Child Adolesc Psychiatry 53:174~187
Faraone SV / 2009 / Using Meta-analysis to compare the efficacy of medications for attention-deficit/hyperactivity disorder in youths / P T 34:678~694
Ganos C / 2015 / Tics and tourette syndrome / Neurol Clin 33:115~136
Jiao F / 2016 / Clinical observation on treatment of Tourette syndrome in Chinese children by clonidine adhesive patch / Eur J Paediatr Neurol 20:80~84
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