지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Objectives In development of Korean addiction treatment guidelines, the aim of this study was to investigate the experts’ consensus regarding current pharmacological practice in treatment of alcohol withdrawal.
Methods Using recommendations from foreign clinical guidelines, which were either lacking in evidence or could not be directly applied to Korea, the executive committee developed a questionnaire consisting of 17 questions. Using a nine-point scale, members of the Korean Addiction Psychiatry, who were experts (n=150) with sufficient experience in treatment of alcohol use disorder,were asked to evaluate the appropriateness of each item on the questionnaire. We classified the experts’ opinion according to three categories, based on the lowest scores of 6.5 or greater as a first-line/preferred treatment, 3.5-6.5 as a second-line/reasonable treatment, and lower than 3.5as a third-line/inappropriate treatment. The consensus was determined by chi-square test (p<0.05). Response rate was 70.4% (81/115).
Results The results of the survey from the experts were as follows: 1) Symptom triggered therapy (STT) was the most appropriate strategy in treatment of alcohol withdrawal (95% CI 7.41-8.04). 2) Prophylactic benzodiazepine was recommended for management of expecting alcohol withdrawal in out-patient-department patients. 3) Among benzodiazepines, lorazepam was the most preferred. 4) For patients with severe withdrawal, lorazepam 7.4 mg/day (95% CI 6.48-8.25, maximum dose=20 mg) was recommended. 5) Risperidone, quetiapine, and haloperidol were the first-line drugs for patients with alcohol withdrawal and combined psychotic symptoms.
6) 127.5 mg (95% CI 111-145) for 2.8 months of prophylactic thiamine and 213.5 mg (95% CI 190-240) for 6.2 months of thiamine for Wernicke-Korsakoff’s syndrome were recommended.
Conclusion We hope that these Korean addiction treatment guidelines, added by the Korean experts’ consensus, will be helpful in promoting the efficacy of treatment for alcohol withdrawal.
목차
등록된 정보가 없습니다.
참고문헌 (27)
참고문헌 신청
/ / Clinical practice guideline for stroke / Cpg.or.kr
Addictionacademy / / Addiction Treatment Guidelines Series
Agreetrust / / Appraisal of Guidelines for Research & Evaluation
American Psychiatric Association / 2000 / Diagnostic and statistical manual of mental disorders / American Psychiatric Association
Bayard M / 2004 / Alcohol withdrawal syndrome / Am Fam Physician 69 : 1443 ~ 1450
Addictionacademy / / Addiction Treatment Guidelines Series
Agreetrust / / Appraisal of Guidelines for Research & Evaluation
American Psychiatric Association / 2000 / Diagnostic and statistical manual of mental disorders / American Psychiatric Association
Bayard M / 2004 / Alcohol withdrawal syndrome / Am Fam Physician 69 : 1443 ~ 1450
이 논문의 저자 정보
최근 본 자료
댓글(0)
0