지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 190 - 195 (6page)
이용수
초록· 키워드
오류제보하기
ObjectiveaaThe aims of this study were to determine whether childhood maltreatment contributes to the occurrence of major depressive disorder (MDD) with bipolarity, and whether there is a relationship between central serotonergic activity, as assessed using loudness dependence of auditory evoked potentials (LDAEP), and childhood maltreatment.
MethodsaaThirty-five MDD patients were stratified according to the presence or absence of childhood trauma into two subgroups, childhood trauma (CT) and no childhood trauma (NCT), using the Korean version of the Childhood Trauma Questionnaire (K-CTQ).
The CT group was subjected to further analysis. Several psychometric ratings were also applied. In addition, auditory processing for the loudness dependence of auditory evoked potentials (LDAEP), which was used as a marker of serotonergic activity, was measured before beginning medication.
ResultsaaThere was a significant difference in total Korean Bipolar Spectrum Disorder Scale score between the CT and NCT groups (t=-2.14, p=0.04). The total K-CTQ score was positively correlated with the total Beck Scale for Suicidal Ideation (BSS) score (r=0.36, p=0.036). In particular, emotional abuse was positively correlated with the total Barratt Impulsiveness Scale (r=0.38, p=0.026), BSS (r=0.38, p=0.025), and Hamilton Depression Rating Scale (HAMD) (r=0.36, p=0.035) scores. There was also a positive correlation between LDAEP and total Hypomania Personality Scale (r=0.49, p=0.02) and HAMD (r=0.58, p=0.004) scores within CT group.
ConclusionaaThe findings of this study support that there is a relationship between childhood maltreatment and bipolarity in patients with MDD.
목차
등록된 정보가 없습니다.
참고문헌 (35)
참고문헌 신청
Pereda N / 2009 / The prevalence of child sexual abuse in community and student samples : a meta-analysis / Clin Psychol Rev 29:328~338
Norman RE / 2012 / The longterm health consequences of child physical abuse, emotional abuse, and neglect: a systematic review and meta-analysis / PLoS Med 9:e1001349
Arnow BA / 2004 / Relationships between childhood maltreatment, adult health and psychiatric outcomes, and medical utilization / J Clin Psychiatry 65(Suppl 12):10~15
Sachs-Ericsson N / 2009 / A review of childhood abuse, health, and pain-related problems: the role of psychiatric disorders and current life stress / J Trauma Dissociation 10:170~188
Fisher HL / 2013 / Interaction between specific forms of childhood maltreatment and the serotonin transporter gene(5-HTT)in recurrent depressive disorder / J Affect Disord 145:136~141
Norman RE / 2012 / The longterm health consequences of child physical abuse, emotional abuse, and neglect: a systematic review and meta-analysis / PLoS Med 9:e1001349
Arnow BA / 2004 / Relationships between childhood maltreatment, adult health and psychiatric outcomes, and medical utilization / J Clin Psychiatry 65(Suppl 12):10~15
Sachs-Ericsson N / 2009 / A review of childhood abuse, health, and pain-related problems: the role of psychiatric disorders and current life stress / J Trauma Dissociation 10:170~188
Fisher HL / 2013 / Interaction between specific forms of childhood maltreatment and the serotonin transporter gene(5-HTT)in recurrent depressive disorder / J Affect Disord 145:136~141
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