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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 829 - 835 (7page)
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초록· 키워드
오류제보하기
Objective This study aimed to investigate the effectiveness and tolerability of the combination of electroconvulsive therapy (ECT) in patients with clozapine-treated schizophrenia. Methods Patients with clozapine-treated schizophrenia during five years of pre-determined period were recruited from Electronic Medical Record. Clinical effects of acute ECT on psychotic symptoms were investigated. We also tried to identify predictive variables requiring maintenance treatment of ECT. Results Fourteen patients received ECT and clozapine and sixteen were treated with clozapine alone. In the ECT group, which could be refined as clozapine-resistance, PANSS total score was significantly reduced by 19.0±9.9 points, corresponding to a reduction rate of 18.5±8.3%. The clinical remission defined as 20% PANSS reduction criteria was achieved at 42.9%. The subscale factors were significantly reduced, among which the negative symptom was the least. There was no difference in demographic and clinical information between patients receiving and not receiving maintenance ECT, and not all patients seemed to need maintenance ECT if clozapine is continued. Conclusion Combination of ECT and clozapine in patients with clozapine-resistant schizophrenia resulted in a rapid and substantial reduction of psychotic symptoms. Further studies are needed to improve the effectiveness and tolerability of ECT.
목차
등록된 정보가 없습니다.
참고문헌 (57)
참고문헌 신청
Weiner RD / 2001 / The Practice of Electroconvulsive Therapy: Recommendations for Treatment, Training, and Privileging (A Task Force Report of the American Psychiatric Association). 2nd Ed.
Huuhka K / 2012 / One-year follow-up after discontinuing maintenance electroconvulsive therapy / J ECT 28:225~228
Fink M / 1996 / Convulsive therapy in schizophrenia? / Schizophr Bull 22:7~39
Chanpattana W / 2006 / ECT for treatment-resistant schizophrenia: a response from the far East to the UK. NICE report / J ECT 22:4~12
Suzuki K / 2007 / Continuation electroconvulsive therapy to prevent relapse of schizophrenia in relapse-prone patients / J ECT 23:204~205
Huuhka K / 2012 / One-year follow-up after discontinuing maintenance electroconvulsive therapy / J ECT 28:225~228
Fink M / 1996 / Convulsive therapy in schizophrenia? / Schizophr Bull 22:7~39
Chanpattana W / 2006 / ECT for treatment-resistant schizophrenia: a response from the far East to the UK. NICE report / J ECT 22:4~12
Suzuki K / 2007 / Continuation electroconvulsive therapy to prevent relapse of schizophrenia in relapse-prone patients / J ECT 23:204~205
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