지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Objectives: Decreased fertility and impaired health owing to early menopause are significant health issues. Smoking is a modifiable health-related behavior that influences menopausal age. We investigated the effects of smoking-associated characteristics on menopausal age in Korean women.
Methods: This study used data from the Korea National Health and Nutrition Examination Survey from 2007 to 2012. Menopausal age in relation to smoking was analyzed as a Kaplan-Meier survival curve for 11 510 women (aged 30 to 65 years). The risk of entering menopause and experiencing early menopause (before age 48) related to smoking were assessed using a Cox proportional hazards model.
Results: The menopausal age among smokers was 0.75 years lower than that among non-smokers (p<0.001). The results of the Cox proportional hazards model showed pre-correction and post-correction risk ratios for entering menopause related to smoking of 1.26 (95% confidence interval [CI], 1.09 to 1.46) and 1.27 (95% CI, 1.10 to 1.47), respectively, and pre-correction and post-correction risk ratios for experiencing early menopause related to smoking of 1.36 (95% CI, 1.03 to 1.80) and 1.40 (95% CI, 1.05 to 1.85), respectively.
Conclusions: Smokers reached menopause earlier than non-smokers, and their risk for experiencing early menopause was higher.
목차
등록된 정보가 없습니다.
참고문헌 (31)
참고문헌 신청
Whelan EA / 1990 / Menstrual and reproductive characteristics and age at natural menopause / Am J Epidemiol 131(4):625~632
van Asselt KM / 2004 / Current smoking at menopause rather than duration determines the onset of natural menopause / Epidemiology 15(5):634~639
Jurisicova A / 2007 / Maternal exposure to polycyclic aromatic hydrocarbons diminishes murine ovarian reserve via induction of Harakiri / J Clin Invest 117(12):3971~3978
Barbieri RL / 1986 / Nicotine, cotinine, and anabasine inhibit aromatase in human trophoblast in vitro / J Clin Invest 77(6):1727~1733
Li S / 2013 / Age at natural menopause in relation to all-cause and cause-specific mortality in a follow-up study of US black women / Maturitas 75(3):246~252
van Asselt KM / 2004 / Current smoking at menopause rather than duration determines the onset of natural menopause / Epidemiology 15(5):634~639
Jurisicova A / 2007 / Maternal exposure to polycyclic aromatic hydrocarbons diminishes murine ovarian reserve via induction of Harakiri / J Clin Invest 117(12):3971~3978
Barbieri RL / 1986 / Nicotine, cotinine, and anabasine inhibit aromatase in human trophoblast in vitro / J Clin Invest 77(6):1727~1733
Li S / 2013 / Age at natural menopause in relation to all-cause and cause-specific mortality in a follow-up study of US black women / Maturitas 75(3):246~252
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