우리나라 성인 남성에서 흡연량과 공복혈당장애 또는 제2형 당뇨병 발생과의 연관성

박창해; 가혁; 임종한; 곽승민; 김환철; 최지호

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자료유형: 학술저널

저자정보: 박창해 가혁 임종한 곽승민 김환철 최지호

저널정보: 대한예방의학회 예방의학회지 예방의학회지 제41권 제4호

발행연도: 2008.1

수록면: 249 - 254 (6page)

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Objectives : To investigate whether smoking and the smoking status are predictors of the incident impaired fasting glucose (IFG) or type 2 diabetes in Korean men. Methods : A cohort of 1,717 Korean men without IFG or diabetes, who underwent annual periodic health examinations for 4 years (2002-2006), were retrospectively investigated. IFG and diabetes were defined as a serum fasting glucose concentration of 100-125 mg/dL and more than 126 mg/dL, respectively. CoxNs proportional hazards model was used to evaluate the association between smoking and development of IFG or type 2 diabetes. Results : A total of 558 cases (32.5%) of incident IFG and 50 cases (2.9%) of diabetes occurred. After controlling for the potential predictors of diabetes, the relative risk for IFG, compared with the never smokers, was 1.02 (95% CI=0.88 to 1.19) for the ever-smokers, 0.96 (95% CI=0.79- 1.16) for those who smoked 1-9 cigarettes/d, 1.15 (95% CI=1.01 to 1.30) for those who smoked 10-19 cigarettes/d, and 1.31 (95% CI=1.10 to 1.57) for those who smoked 20 or more cigarettes/d (the P value for the current smokers was only p<0.002). The respective multivariate adjusted relative risks for type 2 diabetes, compared with the neversmokers, were 1.07 (95% CI=0.64 to 1.92), 1.47 (95% CI=0.71 to 3.04), 1.84 (95% CI=0.92-3.04), and 1.87 (95% CI=1.13-3.67), respectively (the P value for the current smokers was only p=0.004). Conclusions : The smoking status and the number of cigarettes smoked daily are associated with an increased risk for developing IFG or type 2 diabetes in Korean men.

#Smoking #Blood glucose #Type 2 diabetes mellitus

참고문헌 (23)

참고문헌 신청

/ 1997 / Report of the expert committee on the diagnosis and classification of diabetes mellitus / Diabetes Care 20 (7) : 1183 ~ 1197

Alberti, K.G. / 1998 / Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisi

Colditz, G.A. / 1995 / Weight gain as a risk factor for clinical diabetes mellitus in women / Ann Intern Med 122 (7) : 481 ~ 486

Feskens, E.J. / 1989 / Cardiovascular risk factors and the 25-year incidence of diabetes mellitus in middle-aged men / The Zutphen Study. Am J Epidemiol 130 (6) : 1101 ~ 1108

Fujioka, S. / 1987 / Contribution of intra-abdominal fat accumulation to the impairment of glucose and lipid metabolism in human obesity / Metabolism 36 (1) : 54 ~ 59

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