지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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In this study, we measured the chemical shift change of metabolite peaks in the brain-metabolite phantom according to the temperature variation using nuclear magnetic resonance(NMR). The temperature range in NMR system was controled from 25℃ to 80℃(5℃ step) by internal temperature controller. Temperature coefficients of each metabolite peaks were also calculated from the measured chemical shift depending on the temperature. The chemical shift changes depending on temperature were validated by linear regression method for each metabolite peaks. The temperature coefficients of totCr, Cho, Cr, NAA, and Lac were 0.0086, 0.0088, 0.0091, 0.0089, and 0.0088ppm/℃, respectively. This study shows that chemical shift change of brain metabolite and temperature variation have linear relationship each other. This also makes authors believe that brain temperature measurement is possible using MR spectroscopic imaging technique.
목차
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참고문헌 (23)
참고문헌 신청
Cady EB / 1995 / The estimation of local brain temperature by in vivo 1H magnetic resonance spectroscopy / Magn Reson Med 33 : 862 ~ 867
Carter DL / 1998 / Magnetic resonance thermometry during hyperthermia for human high-grade sarcoma / Int J Radiat Oncol Biol Phys 40 : 815 ~ 822
Castillo J / 1998 / Timing for fever-related brain damage in acute ischemic stroke / Stroke 29 : 2455 ~ 2460
Corbett RJ / 1995 / Validation of a noninvasive method to measure brain temperature in vivo using 1H NMR spectroscopy / J Neurochem 64 : 1224 ~ 1230
Daiya Ishigaki / 2009 / Brain Temperature Measured Using Proton MR Spectroscopy Detects Cerebral Hemodynamic Impairment in Patients With Unilateral Chronic Major Cerebral Ar
Carter DL / 1998 / Magnetic resonance thermometry during hyperthermia for human high-grade sarcoma / Int J Radiat Oncol Biol Phys 40 : 815 ~ 822
Castillo J / 1998 / Timing for fever-related brain damage in acute ischemic stroke / Stroke 29 : 2455 ~ 2460
Corbett RJ / 1995 / Validation of a noninvasive method to measure brain temperature in vivo using 1H NMR spectroscopy / J Neurochem 64 : 1224 ~ 1230
Daiya Ishigaki / 2009 / Brain Temperature Measured Using Proton MR Spectroscopy Detects Cerebral Hemodynamic Impairment in Patients With Unilateral Chronic Major Cerebral Ar
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