지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 630 - 634 (5page)
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초록· 키워드
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Background: We aimed to determine the association between platelet indices including plateletcrit (PCT), mean platelet volume (MPV), platelet distribution width (PDW), and proteinuria associated with hypertension (HT) as well as the relative power of each to predict proteinuria.
Methods: The study included 223 patients (68 men and 155 women) with primary HT. PCT, MPV, PDW, and proteinuria levels were measured. The patients were divided into two groups according to proteinuria status based on 24-hr urinary protein excretion: proteinuria (+) group (15 men and 40 women) and proteinuria (-) group (53 men and 115 women).
Results: The mean and SD of platelet count, PDW, PCT, and MPV were 278.8±49.6 ×109/L, 13.5±1.8%, 0.31±0.07%, and 11.3±2.6 fL, respectively. The mean platelet count, PCT, MPV, and PDW were significantly higher in the proteinuria (+) group than in the proteinuria (-) group (P<0.05); there were no significant differences in the other blood parameters between the two groups. The platelet count, PCT, MPV, and PDW were independent risk factors predictive of proteinuria according to a stepwise regression analysis of PDW, PCT, and MPV. PCT was the strongest independent predictor of proteinuria.
Conclusions: The platelet indices PCT, PDW, and MPV were significantly higher in patients with proteinuria than in those without it. Among these three indices, PCT was the strongest predictor of proteinuria.
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Akpinar I / 2014 / Plateletcrit and red cell distribution width are independent predictors of the slow coronary flow phenomenon / J Cardiol 63 : 112 ~ 118
Bekler A / 2015 / Increased platelet distribution width is associated with severity of coronary artery disease in patients with acute coronary syndrome / Angiology 66 : 638
Blann AD / 2003 / Pharmacological modulation of platelet function in hypertension / Hypertension 42 : 1 ~ 7
Boos CJ / 2007 / Assessment of platelet activation indices using the ADVIATM 120 amongst ‘high-risk’ patients with hypertension / Ann Med 39 : 72 ~ 78
Endler G / 2002 / Mean platelet volume is an independent risk factor for myocardial infarction but not for coronary artery disease / Br J Haematol 117 : 399 ~ 404
Bekler A / 2015 / Increased platelet distribution width is associated with severity of coronary artery disease in patients with acute coronary syndrome / Angiology 66 : 638
Blann AD / 2003 / Pharmacological modulation of platelet function in hypertension / Hypertension 42 : 1 ~ 7
Boos CJ / 2007 / Assessment of platelet activation indices using the ADVIATM 120 amongst ‘high-risk’ patients with hypertension / Ann Med 39 : 72 ~ 78
Endler G / 2002 / Mean platelet volume is an independent risk factor for myocardial infarction but not for coronary artery disease / Br J Haematol 117 : 399 ~ 404
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